Tscherne G, Schwarz G
Geburtshilfe Frauenheilkd. 1976 Dec;36(12):1076-81.
Angiography has proved valuable as a method for visualizing the position and extent of trophoblastic tumors. Angiography together with the determination of gonadotropin makes a more exact diagnosis possible and, therefore, an individual therapy. The treatment must be intentionally carried out's the age of the patient plays an important role here. For many cases today, purely conservative therapy with cytostatic drugs is possible. This method was used in 11 female patients with suspected or histologically established trophoblastic tumors. In 4 women, the tumor was suspected a because of the reincrease in HCG excretion following a hydatidiform mole. A metastasizing mole was established histologically in 3 patients and a choriocarcinoma, in 4 patients. A good correspondence was found between angiographic and macroscopic findings in 6 women who underwent surgery. In evaluating control angiograms following chemotherapy, it should be noted that tumors do not recede completely in every case.
血管造影已被证明是一种可视化滋养细胞肿瘤位置和范围的有价值的方法。血管造影与促性腺激素的测定相结合,使得更准确的诊断成为可能,从而实现个体化治疗。治疗必须有意进行,因为患者的年龄在此起着重要作用。如今,对于许多病例,使用细胞毒性药物进行单纯的保守治疗是可行的。该方法用于11例疑似或经组织学确诊为滋养细胞肿瘤的女性患者。在4名女性中,由于葡萄胎后HCG排泄再次升高而怀疑有肿瘤。3例患者经组织学确诊为转移性葡萄胎,4例患者为绒毛膜癌。6例接受手术的女性患者的血管造影结果与宏观检查结果有良好的一致性。在评估化疗后的对照血管造影时,应注意并非每个病例中的肿瘤都会完全消退。