Wang Y H
Xijing Hospital, Xi'an.
Zhong Xi Yi Jie He Za Zhi. 1991 Jun;11(6):343-5, 325.
The authors treated 102 cervical spondylosis patients with jing tong ning granule that made of herbs according to the TCM principle of promoting blood circulation to remove blood stasis. The 9 hemorheological indexes before and after treatment were observed. 15 patients of all were also observed the changes of eyeground microangium. Moreover, the animal experiments were taken in order to test and verify the effects further. The results revealed that the total effective rate was 96.1%. The main hemorheological indexes (eg. blood viscosity and plasma viscosity) showed significant difference in statistics before and after treatment (P less than 0.05, P less than 0.01). The changes of eyeground microangium had significant difference too, (P less than 0.01). The animal experimental results were the same as the clinical ones. Hence, the authors consider that jing tong ning granule had the effects to decrease the blood viscosity, improve microcirculation and accelerate blood flow.
作者采用按中医活血化瘀原则制成的颈痛宁颗粒治疗102例颈椎病患者。观察了治疗前后9项血液流变学指标。全部患者中的15例还观察了眼底微血管的变化。此外,进行了动物实验以进一步验证其效果。结果显示总有效率为96.1%。主要血液流变学指标(如血液粘度和血浆粘度)治疗前后在统计学上有显著差异(P<0.05,P<0.01)。眼底微血管变化也有显著差异(P<0.01)。动物实验结果与临床结果相同。因此,作者认为颈痛宁颗粒具有降低血液粘度、改善微循环和加速血流的作用。