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[椎基底动脉系统脑梗死的病理及病因学研究]

[Pathological and etiological studies on cerebral infarction in the vertebrobasilar arterial system].

作者信息

Tong Q

机构信息

Friendship hospital Beijing.

出版信息

Zhonghua Shen Jing Jing Shen Ke Za Zhi. 1991 Jun;24(3):149-51, 187-8.

PMID:1889323
Abstract

25 cases of cerebral infarcts in vertebrobasilar arterial system are reported. Those were divided into 4 groups: 1. Embolism (10), the causes were NBTE, pulmonary infarct, rheumatic or congenital heart disease, coronary artery disease, respectively, and 2 unknown. 2. Thrombosis (5), the causes were arteriosclerosis, vascular malformations in the basal part of cerebrum. 3. Inflammatory infarcts (3), those were verified from tuberculosis, syphilis and aspergillosis respectively. 4. Lacunar infarcts (7), the causes were considered from hypertension. Pathologically, it was noticed that the location of embolism often situated at the terminal of basilar artery, and that if the embolism was completely obliterated, often a hemorrhagic infarction would follow. But the thrombosis in basilar artery, even the lumen was completely obliterated, any infarct would not follow, if the related collateral circulation was satisfactory. Clinically, the embolism in basilar artery often showed sudden onset, and that the symptoms of brain stem would aggravate quickly, but the thrombosis in basilar artery, if the collateral circulation was satisfactory, and symptom of brain stem might not follow.

摘要

报告了25例椎基底动脉系统脑梗死病例。这些病例分为4组:1. 栓塞(10例),病因分别为非细菌性血栓性心内膜炎、肺梗死、风湿性或先天性心脏病、冠状动脉疾病,另有2例病因不明。2. 血栓形成(5例),病因分别为动脉硬化、大脑底部血管畸形。3. 炎症性梗死(3例),分别由结核、梅毒和曲霉菌病所致。4. 腔隙性梗死(7例),病因考虑为高血压。病理检查发现,栓塞部位常位于基底动脉末端,若栓塞完全阻塞血管,常继发出血性梗死。但基底动脉血栓形成,即使管腔完全阻塞,若相关侧支循环良好,则不会发生梗死。临床上,基底动脉栓塞常表现为突然起病,脑干症状迅速加重,但基底动脉血栓形成,若侧支循环良好,则可能不出现脑干症状。

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