Rauscher H, Popp W, Zwick H
Pulmonary Department, Krankenhaus Lainz, Vienna, Austria.
Eur Respir J. 1991 Jun;4(6):655-9.
Intermittent snoring and cyclic oscillations of heart rate and oxyhaemoglobin saturation (Sao2) are characteristic features of the obstructive sleep apnoea syndrome (OSAS). Thus, overnight recordings of laryngeal sounds and heart rate by a portable device (MESAM) and of Sao2 by oximetry are applicable to screen outpatients for the presence of OSAS. Computerized analysis for time intervals of constant heart rate and intervals between snoring sounds is used by MESAM to quantify respiratory disturbances during sleep. Rapid increases in Sao2 during the postapnoeic hyperventilation period together with the number of desaturations are used by a new software for quantitative analysis of oximetry. To elucidate reliability of results from automatically scored MESAM and oximetry recordings, we compared the four computer calculated respiratory disturbance indices from heart rate (RDIH), snoring (RDIS), resaturations (RDIR) and desaturations (RDID) with the apnoea plus hypopnoea index (AHI) from simultaneously performed polysomnography. The study population consisted of 53 snorers with an AHI of 19.0 +/- 2.6 (median +/- SEM; range 0.7-87.8). Whereas both RDI's from MESAM correlated rather weakly with the AHI from polysomnography (RDIH: r = 0.32, p less than 0.05; RDIS: r = 0.33, p less than 0.05), this correlation was much better for the RDI's from oximetry (RDIR: r = 0.951, RDID: r = 0.93; p much less than 0.0001). Accepting a plus/minus 30 percent difference from the AHI, the RDIR classified 77% of patients correctly, the RDID 62%, the RDIS 32% and the RDIH 23%. In conclusion, results from computerized analysis of oximetry for desaturations and rapid resaturations correlate more closely with polysomnography than those from automatic scoring of MESAM recordings.
间歇性打鼾以及心率和氧合血红蛋白饱和度（Sao2）的周期性波动是阻塞性睡眠呼吸暂停综合征（OSAS）的特征性表现。因此，通过便携式设备（MESAM）对喉音和心率进行整夜记录，并通过血氧测定法记录Sao2，可用于筛查门诊患者是否患有OSAS。MESAM利用计算机分析恒定心率的时间间隔以及打鼾声音之间的间隔，以量化睡眠期间的呼吸紊乱情况。一种用于血氧测定法定量分析的新软件，利用呼吸暂停后过度通气期Sao2的快速升高以及血氧饱和度下降的次数。为了阐明自动评分的MESAM和血氧测定记录结果的可靠性，我们将通过心率（RDIH）、打鼾（RDIS）、再饱和（RDIR）和血氧饱和度下降（RDID）这四项计算机计算得出的呼吸紊乱指数与同时进行的多导睡眠图得出的呼吸暂停加呼吸不足指数（AHI）进行了比较。研究人群包括53名打鼾者，其AHI为19.0±2.6（中位数±标准误；范围0.7 - 87.8）。虽然MESAM的两个RDI与多导睡眠图的AHI相关性较弱（RDIH：r = 0.32，p＜0.05；RDIS：r = 0.33，p＜0.05），但血氧测定法的RDI相关性更好（RDIR：r = 0.951，RDID：r = 0.93；p远＜0.0001）。若接受与AHI相差±30%的差异，则RDIR正确分类了77%的患者，RDID为62%，RDIS为32%，RDIH为23%。总之，计算机化分析血氧测定法得出的血氧饱和度下降和快速再饱和结果与多导睡眠图的相关性比自动评分的MESAM记录结果更紧密。
