Abramson D L, Shaw W W, Kamat B R, Harper A, Rosenberg C R
Department of Surgery, State University of New York Health Science Center, Brooklyn.
J Reconstr Microsurg. 1991 Jul;7(3):199-203. doi: 10.1055/s-2007-1006779.
A low-powered carbon dioxide laser was used to perform 25 vein grafts (50 anastomoses) on the femoral veins of Sprague-Dawley rats. The patency rate, clamp time, and bleeding time were compared with 50 conventional microvascular vein grafts (100 anastomoses). The patency of the laser-assisted anastomoses (LAVA) was 84 percent, while the conventional vein grafts yielded a 94 percent patency rate. The average clamp time and bleeding time for the LAVA were 47.2 min and 4.88 sec, respectively, while the conventional anastomoses required 57.6 min and had an average bleeding time of 9.44 sec. Histologically, both specimens healed at the same rate, but the laser-assisted anastomoses produced less inflammation and granulation tissue. These results suggest that the laser has potential as a tool for clinical application in microsurgery. In addition, the 94 percent patency rate achieved with the vein interposition graft would suggest that a decrease in the tension across the anastomosis can improve patency.
使用低功率二氧化碳激光对Sprague-Dawley大鼠的股静脉进行25次静脉移植（50个吻合口）。将通畅率、夹闭时间和出血时间与50次传统微血管静脉移植（100个吻合口）进行比较。激光辅助吻合术（LAVA）的通畅率为84%，而传统静脉移植的通畅率为94%。LAVA的平均夹闭时间和出血时间分别为47.2分钟和4.88秒，而传统吻合术需要57.6分钟，平均出血时间为9.44秒。组织学上，两个标本的愈合速度相同，但激光辅助吻合术产生的炎症和肉芽组织较少。这些结果表明，激光有潜力作为一种工具应用于显微外科临床。此外，静脉搭桥移植术达到的94%的通畅率表明，吻合口处张力的降低可以提高通畅率。
