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[一名肝硬化女性患者由小肠结肠炎耶尔森菌引起的脓毒症]

[Sepsis caused by Yersinia enterocolitica in a female patient with liver cirrhosis].

作者信息

Radman I, Kalenić S, Stoiljković I, Perković D, Labar B

机构信息

Zavod za hematologiju, KBC, Medicinski fakultet Sveucilista u Zagrebu.

出版信息

Lijec Vjesn. 1991 Jan-Feb;113(1-2):34-6.

PMID:1890909
Abstract

As a primarily intestinal pathogen. Yersinia enterocolitica (Y. e.) may cause generalized infection in patients with malignant and other serious diseases or immunodeficient subjects. In certain conditions, elevated serum and tissue iron concentrations represent an additional risk factor for systemic infection with this opportunistic bacterium. In our patient, Y. e. septicemia developed during liver cirrhosis decompensation. Clinical signs of infection were alleviated by appropriate antibiotic therapy (gentamycin, cefuroxime), but as septicemia had been present for several days prior to therapy, it aggravated the patient's general condition, which entailed the development of hepatorenal syndrome and eventually lethal outcome.

摘要

作为一种主要的肠道病原体,小肠结肠炎耶尔森菌(Y. e.)可在患有恶性疾病和其他严重疾病的患者或免疫缺陷受试者中引起全身感染。在某些情况下,血清和组织铁浓度升高是这种机会性细菌发生全身感染的另一个危险因素。在我们的患者中,Y. e.败血症在肝硬化失代偿期发生。通过适当的抗生素治疗(庆大霉素、头孢呋辛),感染的临床症状得到缓解,但由于败血症在治疗前已存在数天,它加重了患者的一般状况,导致肝肾综合征的发生并最终导致致命后果。

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