Smirnova O V, Saliev V P, Klemparskaia N N, Dobronravova N N
Med Radiol (Mosk). 1991;36(8):16-9.
The theoretical basis of this work is the development of autosensitization in exposure to ionizing radiation and well-known desensitizing action of sulphuric agents. To reduce clinical manifestations of a reaction to combined radiotherapy 34 women with diagnosis of cervical cancer (stages I and II) were given 0.5-1 g of purified sulphur mixed with 0.25 g of glucose in the morning every 2-3 hours before irradiation, per os; 24 patients received placebo (a mixture of egg powder with glucose), in 21 patients no protective means were used. All 79 patients were given unified adjuvant therapy (polyvitamins, leukogens, folic acid) and diet No 15. A significant decrease in the reaction to therapeutic irradiation was noted in the study group. No side-effects were observed.
这项工作的理论基础是电离辐射暴露中自身致敏作用的发展以及硫酸制剂广为人知的脱敏作用。为减轻联合放射治疗反应的临床表现，对34例诊断为宫颈癌（I期和II期）的女性，在放疗前每2 - 3小时口服一次0.5 - 1克纯化硫与0.25克葡萄糖的混合物；24例患者接受安慰剂（蛋粉与葡萄糖的混合物），21例患者未使用任何保护手段。所有79例患者均接受统一的辅助治疗（多种维生素、升白细胞药、叶酸）和15号饮食。研究组中观察到对治疗性照射的反应显著降低。未观察到副作用。
