Doshchenko V N
Med Radiol (Mosk). 1991;36(8):38-40.
The paper is concerned with analysis of all lethal outcomes in a followed-up group of patients with chronic radiation sickness (931 patients) from external occupational gamma irradiation. In a majority of cases over a 2-2.5 year period a mean dose of total irradiation was 3.26 +/- 0.13 Gy. During a follow-up period of 37 years 177 patients died. Only 2 patients (2.2%) died of chronic radiation sickness resulting from anaplastic anemia. In the first decade (1952-1961) malignant neoplasia, including leukemia accounted for 42.2%; in the second decade the rate for leukemia was 26.2 decreasing to 5.2%; the rates for tumors were 18.4, 20.6, 23.5%, those for CHD were 7.7-41.8%. Despite high doses of irradiation the tumor mortality rate was 22.6%, coinciding with that in industrial countries (15-23%).
本文关注对一组职业性外照射慢性放射病患者(931例)随访期间所有致死结局的分析。在大多数情况下,经过2至2.5年,总照射平均剂量为3.26±0.13戈瑞。在37年的随访期内,177例患者死亡。仅2例(2.2%)死于再生障碍性贫血所致的慢性放射病。在第一个十年(1952 - 1961年),包括白血病在内的恶性肿瘤占42.2%;在第二个十年,白血病发生率为26.2%,降至5.2%;肿瘤发生率分别为18.4%、20.6%、23.5%,冠心病发生率为7.7% - 41.8%。尽管照射剂量很高,但肿瘤死亡率为22.6%,与工业国家的死亡率(15% - 23%)相符。