Nakaya S
Jpn J Surg. 1976 Sep;6(3):126-36. doi: 10.1007/BF02468784.
In spite of the extensive studies on glucose metabolism in surgical field, the postoperative renal and hepatic glucose metabolism and their interrelation have not been reported. The present study was undertaken to interrelate the metabolic states in the kidney and the liver in total gastrectomized dogs. In the kidney, the glycolysis was inhibited in the early postoperative stage whereas the gluconeogenesis was activated. In the late postoperative stage the glycolysis remained slightly inhibited, while the gluconeogenesis remained activated. In the liver, in the early postoperative stage the glycolysis was inhibited, whereas the gluconeogenesis was activated. The glycolysis in the late postoperative stage returned to the preoperative stage, while the gluconeogenesis remained inhibited. The gluconeogenesis in both kidney and liver was disturbed in the early postoperative stage while they were restored, but were reversed, in the late postoperative stage.
尽管对外科领域的葡萄糖代谢进行了广泛研究，但术后肾脏和肝脏的葡萄糖代谢及其相互关系尚未见报道。本研究旨在探讨全胃切除犬肾脏和肝脏的代谢状态之间的相互关系。在肾脏中，术后早期糖酵解受到抑制，而糖异生被激活。术后晚期糖酵解仍略有抑制，而糖异生仍被激活。在肝脏中，术后早期糖酵解受到抑制，而糖异生被激活。术后晚期糖酵解恢复到术前水平，而糖异生仍受到抑制。肾脏和肝脏的糖异生在术后早期均受到干扰，但在术后晚期恢复但发生了逆转。
