Patitsas C, Rockwood E J, Meisler D M, McMahon J T
Department of Ophthalmology, Cleveland Clinic Foundation, OH 44195-5024.
Ophthalmic Surg. 1991 Jul;22(7):412-3.
We present a case of infectious crystalline keratopathy occurring after 5-fluorouracil filtering surgery. The patient had discrete, branching, white crystalline lesions in the anterior corneal stroma. Cultures grew Streptococcus viridans, and gram-positive cocci were demonstrated in corneal tissue biopsy specimens. Toxic and immunosuppressive properties of 5-fluorouracil may have participated in the pathogenesis of the infectious crystalline keratitis.
我们报告一例5-氟尿嘧啶滤过性手术后发生的感染性结晶性角膜病变。患者角膜前基质有散在、分支状的白色结晶性病变。培养物中生长出草绿色链球菌，角膜组织活检标本中发现革兰氏阳性球菌。5-氟尿嘧啶的毒性和免疫抑制特性可能参与了感染性结晶性角膜炎的发病机制。
