Nunez D A
Dept. of O.R.L., University of Leeds, United Kingdom.
Rhinology. 1991 Jun;29(2):99-103.
Intracranial abscesses secondary to rhinosinugenic disease are uncommon and the incidence is poorly documented. It is generally believed that individuals at risk of developing this complication can be identified by presenting clinical features. A ten year retrospective Scottish national survey 1976-1985 of intracranial abscesses was carried out. Clinical and or radiological evidence of nasal/paranasal aetiology in abscesses localised to the frontal lobe, extradural or subdural spaces allowed 23 surgery or autopsy confirmed abscesses to be classified as rhinosinugenic. 12 abscesses occurred in individuals aged 0-19 years, two in patients with risk factors for intracranial spread, 8 of 11 adults had similar predisposing features (p less than 0.01). This is a rare complication and individuals at risk in the first two decades of life can seldom be identified prospectively on clinical grounds.
鼻源性疾病继发的颅内脓肿并不常见，其发病率的文献记载较少。一般认为，可通过呈现的临床特征来识别有发生这种并发症风险的个体。对1976年至1985年期间的颅内脓肿进行了一项为期十年的苏格兰全国回顾性调查。对于位于额叶、硬膜外或硬膜下间隙的脓肿，若有鼻/鼻窦病因的临床和/或放射学证据，则23例经手术或尸检证实的脓肿可归类为鼻源性。12例脓肿发生在0至19岁的个体中，2例发生在有颅内扩散危险因素的患者中，11例成年人中有8例有类似的易感特征（p小于0.01）。这是一种罕见的并发症，临床上很少能前瞻性地识别出生命最初二十年中有风险的个体。
