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[单纯性胆石症及合并炎症过程的胆石症患者的细胞-体液免疫因子]

[The cellular-humoral immune factors of patients with cholelithiasis uncomplicated and complicated by an inflammatory process].

作者信息

Petrova D, Mikhaĭlova A, Kolarski V

出版信息

Vutr Boles. 1991;30(2):80-5.

PMID:1891909
Abstract

82 patients-10 p. with uncomplicated cholelithiasis, 8 p. with chronic calculous cholecystitis, 34 p. with choledocholithiasis with stenosing papillo-odditis--and 30 healthy controls were examined, with monoclonal antibodies of the firm "Becton-Dickinson". The following immunocompetent cellular clones and subclones were examined: CD3+, CD16+, CD4+, CD8+, CD19+ CD4/CD8, HLA-DR+, CD3+. The results were read with analyzer for fluorescently marked activated cell clones "FACS-TAR". The serum IgA, IgM, IgG, C3-C4 complement fractions and circulating immune complexes were also examined. The analysis of the results shows that in the complicated cases of cholelithiasis with an inflammatory process in the biliary ducts several humoral and cellular immune factors take part.

摘要

82例患者——10例单纯性胆石症患者、8例慢性结石性胆囊炎患者、34例伴有乳头狭窄性胆管炎的胆总管结石患者——以及30名健康对照者接受了检查,使用的是“贝克顿-迪金森”公司的单克隆抗体。检测了以下免疫活性细胞克隆和亚克隆:CD3+、CD16+、CD4+、CD8+、CD19+、CD4/CD8、HLA-DR+、CD3+。结果通过荧光标记活化细胞克隆分析仪“FACS-TAR”读取。还检测了血清IgA、IgM、IgG、C3 - C4补体成分和循环免疫复合物。结果分析表明,在伴有胆管炎症过程的复杂胆石症病例中,多种体液和细胞免疫因子参与其中。

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