Breisblatt W M, Ruffner R J, Uretsky B F, Reddy P S
Division of Cardiology, University of Pittsburgh, Pennsylvania.
Angiology. 1991 Aug;42(8):607-13. doi: 10.1177/000331979104200802.
Percutaneous transluminal coronary angioplasty was performed at the time of the diagnostic catheterization in 188 patients (215 lesions) at a University Hospital in order to assess the efficacy of this approach and the potential role it should play in the evaluation and treatment of patients. Patients either presented for diagnostic catheterization for evaluation of stable coronary disease (79 patients) or for unstable or new onset anginal symptoms (109 patients). Lesions were graded as to whether they were simple or complex; and post angioplasty films were reviewed for success rate, and degree of revascularization. Patients who were referred for stable anginal symptoms had a slightly higher success rate (91%) compared to those who were referred for new onset or more unstable symptomatology (85%, p = ns). Additionally, lesions morphology was judged to be more complex in unstable patients, as 67% had complex lesions with the presence of thrombus or ulcerated plaque in 56% of these stenoses. Angioplasty success was high for simple lesions in all patients, but was most unfavorable for complex stenoses in patients who presented with unstable symptoms (81% success rate). In patients who presented with new onset or unstable symptoms multivessel disease was present in 69% and angioplasty was more often geared at dilating a culprit stenosis leaving only 49% of these patients with complete revascularization. On the other hand, in 76% of those patients who presented with stable angina complete revascularization was a common outcome. Length of hospital stay was considerably shorter at 2.9 +/- 0.8 days in those patients who presented with stable symptoms.(ABSTRACT TRUNCATED AT 250 WORDS)
在一所大学医院,对188例患者(215处病变)进行了诊断性心导管插入术时的经皮腔内冠状动脉成形术,以评估该方法的疗效及其在患者评估和治疗中应发挥的潜在作用。患者要么因评估稳定型冠心病前来进行诊断性心导管插入术(79例患者),要么因不稳定型或新发心绞痛症状前来就诊(109例患者)。病变根据简单或复杂程度进行分级;术后复查血管成形术影片以评估成功率和血运重建程度。因稳定型心绞痛症状前来就诊的患者成功率略高(91%),而因新发或更不稳定症状前来就诊的患者成功率为85%(p=无显著差异)。此外,不稳定患者的病变形态被判定更为复杂,因为67%的患者有复杂病变,其中56%的狭窄部位存在血栓或溃疡斑块。所有患者中简单病变的血管成形术成功率较高,但对于有不稳定症状的患者,复杂狭窄的成功率最不理想(成功率81%)。因新发或不稳定症状前来就诊的患者中,69%存在多支血管病变,血管成形术更多是针对扩张罪犯病变,只有49%的此类患者实现了完全血运重建。另一方面,在因稳定型心绞痛前来就诊的患者中,76%的患者实现完全血运重建是常见结果。有稳定症状的患者住院时间明显更短,为2.9±0.8天。(摘要截断于250字)