Kumar Milind, Goyal Shikha, Bahl Amit, Das Prasenjit, Sharma D N, Ray Ruma, Rath G K
Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi-110 029, India.
J Cancer Res Ther. 2008 Jul-Sep;4(3):131-3. doi: 10.4103/0973-1482.43146.
Sarcomatoid carcinomas are rare tumors. These tumors have been reported at other sites, but head and neck origin is extremely uncommon. We report here a rare case of sarcomatoid carcinoma involving the maxilla. Only four such cases with maxillary origin have been discussed in English literature earlier. As compared to squamous cell carcinoma of maxilla, this variant is associated with poor prognosis and advanced disease at presentation, as was also seen in our case. There are no standard recommendations for management owing to the rarity of this histology. Surgery and radiotherapy form the mainstays of treatment. Exploration of the role of chemotherapy and novel targeted therapy agents is warranted in order to improve treatment results.
肉瘤样癌是罕见肿瘤。这些肿瘤在其他部位已有报道,但头颈部起源极为罕见。我们在此报告一例累及上颌骨的罕见肉瘤样癌病例。此前英文文献中仅讨论过4例上颌骨起源的此类病例。与上颌骨鳞状细胞癌相比,这种变体在就诊时预后较差且疾病进展,我们的病例也是如此。由于这种组织学类型罕见,目前尚无标准的治疗建议。手术和放疗是主要治疗方法。为了改善治疗效果,有必要探索化疗和新型靶向治疗药物的作用。