Kalogiannidis I, Papanikolaou A, Xanthakis I, Makedos A, Prapas N
4th Department of Obstetrics and Gynecology, Hippokratio Hospital, Aristotles University of Thessaloniki, Greece.
Hippokratia. 2008 Jul;12(3):181-5.
The association of ovarian malignancy with dermatomyositis (DM) is well established from previous reports, while the relationship with polymyositis (PM) is rare.
We report a case of a 50 years old nulliparous woman who developed clear cell ovarian cancer four years after the PM diagnosis. The patient presented with deep lower abdominal pain and distension. CA-125 was elevated and the preoperative MRI showed pelvic tumor occupying the Douglas pouch. Exploratory laparotomy revealed a gross mass of clear cell ovarian carcinoma.
Physicians must be alert of the possibility of malignancy in patients with a previous diagnosis of polymyositis.
既往报道已充分证实卵巢恶性肿瘤与皮肌炎(DM)之间存在关联,而与多发性肌炎(PM)的关系则较为罕见。
我们报告一例50岁未生育女性,在诊断为PM四年后发生了透明细胞卵巢癌。患者出现下腹部深部疼痛和腹胀。CA-125升高,术前MRI显示盆腔肿瘤占据道格拉斯窝。剖腹探查发现一个肉眼可见的透明细胞卵巢癌肿块。
医生必须警惕既往诊断为多发性肌炎的患者发生恶性肿瘤的可能性。