Jović Rajko M, Mitrović Slobodan, Janjević Dusica, Dragicević Danijela, Canji Karol
Medicinski fakultet, Klinicki centar Vojvodine, Klinika za bolesti uva, grla i nosa, 21000 Novi Sad, Hajduk Veljkova 1-7.
Med Pregl. 2008;61 Suppl 2:51-6.
The aim of this study is to show our experience in using the endo-extralaryngeal laterofixation of vocal cords in treatment of bilateral recurrent laryngeal nerve palsy, and to point out the difficulties and complications of this procedure and the ways of their managing.
During the period from 2003 to 2006, 14 patients with bilateral palsy of the recurrent laryngeal nerve were treated with method of Lichtenberger's endo-extra laryngeal laterofixation of the vocal cord The patients were 12 female and 2 male from 26 to 78 (average 57.4) years old. The earliest intervention was performed 8 day after the onset of paresis and not later than 40 days.
In 11/14 (78.6%) of the patients bilateral palsy of the recurrent laryngeal nerve occured as a result of thyroid gland surgery. At the admission 2 (14.3%) patients had tracheostomy while 12 (85.7%) had no tracheostomy. Edema was the most often complication of the endo extra laryngeal laterofixation and it appeared in 8/14 (57.1%) patients. The earliest swelling of the laryngeal tissue was recorded on the first postoperative day and the latest one started 7 days after the intervention. Edema developed in 7/11 (63.6%) after total thyreoidectomy, in 1/3 (33.3%) with traumatic injuries in the neck Because of progression of the edema which provoked narrowing of the airway at the laryngeal level tracheostoma was peformed in 2 patients. Inflammation of laryngeal tissue with sudden obstruction of the airway resulted in death in one patient. Malposition of the thread toward the midle part of the vocal cord happened very often if intervention was not performed in JET ventilation anesthesia. The vocal card function was repaired bilaterally in 2 patients and unilaterally in 1 patient (the total being 3 out of 14 patients, i.e. 21.4%) four months after the laterofixation, and the threads were removed. Lung functional test showed the increase in average value PEF% from 26.53 before to 39.43 after laterofixation, and PIF from 0.83 before to 1.19 after intervention. Resistance R% in the upper airway decreased from the average 257.95 as before to 215.83 after the intervention, while the index FEV1.0/PEF (ml/L/min) remained almost the same before 13.25 and after the intervention 13.50 and that showed that the upper airway obstruction, in spite of good clinical tolerance by the patients, still persisted in all patients after the laterofixation.
Lichtenberger's endo-extra laryngeal laterofixation of the vocal cord is a good alternative method for bilateral palsy of the recurrent laryngeal nerve which provide sufficient upper airway without tracheostomy.
本研究的目的是展示我们在使用声带内-外喉侧方固定术治疗双侧喉返神经麻痹方面的经验,并指出该手术的困难、并发症及其处理方法。
2003年至2006年期间,采用利希滕贝格氏声带内-外喉侧方固定术治疗14例双侧喉返神经麻痹患者。患者中12例为女性,2例为男性,年龄在26至78岁之间(平均57.4岁)。最早在麻痹发作后8天进行干预,且不迟于40天。
14例患者中有11例(78.6%)双侧喉返神经麻痹是甲状腺手术所致。入院时,2例(14.3%)患者已行气管切开术,12例(85.7%)未行气管切开术。水肿是内-外喉侧方固定术最常见的并发症,14例患者中有8例(57.1%)出现。最早在术后第1天记录到喉部组织肿胀,最晚在干预后7天出现。全甲状腺切除术后7例(63.6%)出现水肿,颈部外伤患者中有1例(33.3%)出现水肿。由于水肿进展导致喉水平气道狭窄,2例患者行气管造口术。1例患者因喉部组织炎症伴气道突然阻塞死亡。若不在喷射通气麻醉下进行干预,丝线向声带中部移位的情况很常见。侧方固定术后4个月,2例患者双侧声带功能恢复,1例患者单侧恢复(14例患者中共3例,即21.4%),并取出丝线。肺功能测试显示,平均呼气峰流速百分比(PEF%)从固定术前的26.53升至术后的39.43,吸气峰流速(PIF)从术前的0.83升至术后的1.19。上气道阻力百分比(R%)从术前平均257.95降至术后的215.83,而第一秒用力呼气容积与呼气峰流速比值(FEV1.0/PEF,ml/L/min)在术前为13.25,术后为13.50,几乎保持不变,这表明尽管患者临床耐受性良好,但侧方固定术后所有患者上气道梗阻仍然存在。
利希滕贝格氏声带内-外喉侧方固定术是治疗双侧喉返神经麻痹的一种很好的替代方法,可在不行气管切开术的情况下提供足够的上气道。