Lechtenberg R, Vaida G A
Neurology. 1977 Jan;27(1):55-9. doi: 10.1212/wnl.27.1.55.
Four cases of spinal cord schistosomiasis were characterized by paraparesis, sensory loss, and sphincter disturbances progressing over hours to days. One patient showed deterioration over months and remission after laminectomy, followed by the typical, rapidly progressive deficits. Biopsies on two patients showed granulomatous and necrotizing myelitis. Spontaneous improvement and unremitting deterioration, despite chemotherapy, make evaluation of treatment difficult. A survey of all previously reported cases provided no consistent pattern of response to any treatment modalities. Laminectomy for decompression and diagnosis, administration of antischistosomal medications, and high-dose oral prednisone early in the illness are recommended.
4例脊髓血吸虫病的特点是轻截瘫、感觉丧失和括约肌功能障碍，在数小时至数天内逐渐发展。1例患者在数月内病情恶化，行椎板切除术后缓解，随后出现典型的快速进展性神经功能缺损。2例患者的活检显示肉芽肿性和坏死性脊髓炎。尽管进行了化疗，但病情仍有自发改善和持续恶化的情况，这使得治疗评估变得困难。对所有既往报道病例的调查未发现对任何治疗方式有一致的反应模式。建议在疾病早期行椎板切除术以减压和诊断，给予抗血吸虫药物，并使用大剂量口服泼尼松。
