Heldal K, Svendsen E, Maehle B O
Department of Pathology, Gade Institute, University of Bergen, Norway.
APMIS. 1991 Sep;99(9):773-9. doi: 10.1111/j.1699-0463.1991.tb01259.x.
The degree of intimal thickening, folding of the internal elastic lamina (IEL) and luminal radius/wall thickness ratio (RWR) have been compared between predilectional sites and a non-predilectional site for atherosclerosis in human basilar arteries. The findings are compatible with the hypothesis that a low degree of folding and a high RWR facilitate intimal thickening. A negative correlation between the fold index and intimal thickening index and a positive correlation between RWR index and intimal thickening index were found. Predilectional areas also have lower fold indices and higher RWR in younger subjects prior to any intimal thickening development.
在人类基底动脉中，对动脉粥样硬化的好发部位和非好发部位的内膜增厚程度、内弹性膜（IEL）折叠情况以及管腔半径/壁厚比（RWR）进行了比较。这些发现与以下假设相符：低程度的折叠和高RWR会促进内膜增厚。研究发现折叠指数与内膜增厚指数之间呈负相关，RWR指数与内膜增厚指数之间呈正相关。在任何内膜增厚发展之前，年轻受试者的好发区域也具有较低的折叠指数和较高的RWR。
