Nystrom Michael J, Caughey Aaron B, Lyell Deirdre J, Druzin Maurice L, El-Sayed Yasser Y
Department of Obstetrics and Gynecology, Stanford University Medical Center, Stanford, CA, USA.
Am J Obstet Gynecol. 2008 Oct;199(4):385.e1-5. doi: 10.1016/j.ajog.2008.06.065.
To investigate whether perinatal outcomes among interracial Asian-white couples are different than among Asian-Asian and white-white couples.
This was a retrospective study of Asian, white, and Asian-white couples delivered at the Lucile Packard Children's Hospital from 2000-2005. Asian-white couples were subdivided into white-mother/Asian-father or Asian-mother/white-father. Perinatal outcomes included gestational diabetes, hypertensive disorders of pregnancy, preterm delivery, birth weight >4000 g and <2500 g, and cesarean delivery.
In the study population of 868 Asian-white, 3226 Asian, and 5575 white couples there were significant outcome differences. Compared with white couples, Asian-white couples had an increased incidence of gestational diabetes (aOR 2.4 for white-mother/Asian-father and aOR 2.6 for Asian-mother/white-father), though not as high as Asian couples (aOR 4.7). Asian-white couples had larger babies (median 3360 g for Asian-mother/white-father and 3320 g for white-mother/Asian-father vs 3210 g for Asian, P < .001), but only Asian-mother/white-father couples had an increased rate of cesarean delivery (aOR 1.3-2.0).
Significant differences in perinatal outcomes exist between Asian, white, and interracial Asian-white couples.
调查亚裔与白人跨种族夫妇的围产期结局是否与亚裔亚裔夫妇和白人白人夫妇不同。
这是一项对2000年至2005年在露西尔·帕卡德儿童医院分娩的亚裔、白人和亚裔与白人跨种族夫妇的回顾性研究。亚裔与白人跨种族夫妇被细分为白人母亲/亚裔父亲或亚裔母亲/白人父亲。围产期结局包括妊娠期糖尿病、妊娠高血压疾病、早产、出生体重>4000克和<2500克以及剖宫产。
在868对亚裔与白人跨种族、3226对亚裔和5575对白人生育夫妇的研究人群中,存在显著的结局差异。与白人夫妇相比,亚裔与白人跨种族夫妇妊娠期糖尿病的发病率有所增加(白人母亲/亚裔父亲的调整后比值比为2.4,亚裔母亲/白人父亲的调整后比值比为2.6),但不如亚裔夫妇高(调整后比值比为4.7)。亚裔与白人跨种族夫妇的婴儿体重更大(亚裔母亲/白人父亲的中位数为3360克,白人母亲/亚裔父亲的中位数为3320克,而亚裔为3210克,P<.001),但只有亚裔母亲/白人父亲夫妇的剖宫产率有所增加(调整后比值比为1.3 - 2.0)。
亚裔、白人和亚裔与白人跨种族夫妇之间的围产期结局存在显著差异。