Hillman Bruce J, Gatsonis Constantine
Department of Radiology, University of Virginia, Charlottesville, VA 22908, USA.
Semin Oncol. 2008 Oct;35(5):460-9. doi: 10.1053/j.seminoncol.2008.07.010.
The American College of Radiology Imaging Network (ACRIN) is the youngest of the National Cancer Institute (NCI) cooperative groups. ACRIN trials are directed towards evaluating the applications of diagnostic imaging and image-guided treatment to cancer. As ACRIN begins its third funding cycle, the organization is increasingly emphasizing several themes: linking imaging surveillance to pre-imaging testing for disease to improve the efficiency of cancer screening; the evaluation of imaging tests as biomarkers for molecular and physiologic processes in cancer; the standardization and validation of imaging tests to predict and monitor response to treatment; improved characterization of the extent and biology of cancer; and the translation of new emerging technologies from first-in-human testing to multicenter trials. ACRIN is poised to pursue its own research agenda, collaborate with other research entities to address key issues in cancer care, and place at the service of the other cooperative groups its electronic infrastructure to improve imaging in therapeutic trials. ACRIN's pursuit of its unique mission as the sole cooperative group directed principally toward diagnosis has made the network an integral part of the cancer research community.
美国放射学会影像网络（ACRIN）是美国国立癌症研究所（NCI）合作组中最年轻的一个。ACRIN开展的试验旨在评估诊断成像及图像引导治疗在癌症方面的应用。随着ACRIN进入其第三个资助周期，该组织越来越强调几个主题：将成像监测与疾病的成像前检测相联系，以提高癌症筛查的效率；评估成像检测作为癌症分子和生理过程生物标志物的作用；成像检测的标准化和验证，以预测和监测治疗反应；更好地描述癌症的范围和生物学特性；以及将新兴技术从首次人体试验转化为多中心试验。ACRIN准备推行自己的研究议程，与其他研究实体合作以解决癌症治疗中的关键问题，并将其电子基础设施用于为其他合作组服务，以改善治疗试验中的成像。ACRIN作为主要致力于诊断的唯一合作组，追求其独特使命，这使该网络成为癌症研究界不可或缺的一部分。
