Godard M, Forest A, Verny M, Boddaert J
Centre de gériatrie, hôpital Pitié-Salpêtrière, AP-HP, UPMC, Paris, France.
Transfus Clin Biol. 2008 Nov;15(5):212-3. doi: 10.1016/j.tracli.2008.09.021. Epub 2008 Oct 18.
The frequency of anemia is responsible of a frequent use of transfusion in elderly patients. However, transfusion in elderly patients requires several warnings. First, semiology of elderly patients is characterized with atypical clinical signs, and anemia tolerance is often difficult to appreciate. Second, numerous comorbidities make of elderly patients an heterogeneous population, in which guidelines are poorly applicable. Last, elderly patients are particularly sensitive to iatrogenic events, and the haemodynamic overload related to transfusion has to be carefully managed. All these difficulties raise the need of prospective studies on transfusion in elderly patients to validate clinical practice.
贫血的发生率导致老年患者频繁输血。然而，老年患者输血需要注意几个问题。首先，老年患者的症状学表现为非典型临床体征，贫血耐受性往往难以评估。其次，众多合并症使老年患者成为一个异质性群体，在这个群体中指南的适用性较差。最后，老年患者对医源性事件特别敏感，与输血相关的血流动力学超负荷必须得到谨慎处理。所有这些困难都增加了对老年患者输血进行前瞻性研究以验证临床实践的必要性。
