Talaty Nari, Mulligan Christopher C, Justes Dina R, Jackson Ayanna U, Noll Robert J, Cooks R Graham
Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA.
Analyst. 2008 Nov;133(11):1532-40. doi: 10.1039/b807934j. Epub 2008 Aug 8.
Desorption electrospray ionization (DESI) is applied to the rapid, in-situ, direct qualitative and quantitative analysis of mixtures of explosives and drugs from a variety of fabrics, including cotton, silk, denim, polyester, rayon, spandex, leather and their blends. The compounds analyzed were explosives: trinitrohexahydro-1,3,5-triazine (RDX), octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX), 2,4,6-trinitrotoluene (TNT), pentaerythritol tetranitrate (PETN) and the drugs of abuse: heroin, cocaine, and methamphetamine. Limits of detection are in the picogram range. DESI analyses were performed without sample preparation and carried out in the presence of common interfering chemical matrices, such as insect repellant, urine, and topical lotions. Spatial and depth profiling was investigated to examine the depth of penetration and lateral resolution. DESI was also used to examine cotton transfer swabs used for travel security sample collection in the screening process. High throughput quantitative analysis of fabric surfaces for targeted analytes is also reported.
解吸电喷雾电离（DESI）用于对来自各种织物（包括棉、丝绸、牛仔布、聚酯、人造丝、氨纶、皮革及其混合物）的炸药和毒品混合物进行快速、原位、直接的定性和定量分析。所分析的化合物包括炸药：六氢-1,3,5-三硝基-1,3,5-三嗪（RDX）、八氢-1,3,5,7-四硝基-1,3,5,7-四氮杂环辛烷（HMX）、2,4,6-三硝基甲苯（TNT）、季戊四醇四硝酸酯（PETN）以及滥用药物：海洛因、可卡因和甲基苯丙胺。检测限在皮克范围内。DESI分析无需样品制备，且在常见干扰化学基质（如驱虫剂、尿液和外用洗剂）存在的情况下进行。研究了空间和深度剖析，以检查渗透深度和横向分辨率。DESI还用于检查在筛查过程中用于旅行安全样品采集的棉花转移拭子。还报告了对织物表面目标分析物的高通量定量分析。
