• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[后颅窝血管外皮细胞瘤:病例报告]

[Hemangiopericytoma of the posterior fossa: case report].

作者信息

Gutiérrez-González R, Boto G R, Pérez-Zamarrón A, Rivero-Garvía M

机构信息

Servicio de Neurocirugía, Hospital Clínico San Carlos, Madrid, Spain.

出版信息

Neurocirugia (Astur). 2008 Oct;19(5):446-52.

PMID:18936862
Abstract

Hemangiopericytoma is an uncommon mesenchymal neoplasm arising from Zimmerman's pericytes, which usually locates in soft tissues. Meningeal hemangiopericytoma accounts for less than 1% of all intracranial tumours. Typically, it behaves aggressively, showing distinct tendency to recur locally or distantly along the neural axis and to present extraneural metastases. We describe a 74-year-old patient who presented unspecific symptoms and whose physical exam revealed a painless retroauricular mass which was adhered to skin. Neuroimaging studies showed a large posterior fossa tumour with intense enhancement after contrast infusion that caused striking occipital-mastoid osteolysis and which was exclusively fed by external carotid artery branches. The patient underwent gross total resection of the tumour, and once the histological diagnosis of hemangiopericytoma was confirmed, she underwent initial adjuvant radiotherapy. Sixteen months after surgery, the patient remains recurrence free. The treatment of choice of intracranial hemangiopericytoma is gross total resection, which must be attempted when technically feasible, followed by adjuvant radiotherapy providing total doses over 50 Gy. This combination has demonstrated increasing recurrence- free interval in these patients. Close and longterm follow-up is mandatory in order to achieve early diagnosis of recurrence or metastases in these patients, since they can appear several years, even decades, after initial proper treatment.

摘要

血管外皮细胞瘤是一种罕见的间叶性肿瘤,起源于齐默尔曼周细胞,通常位于软组织中。脑膜血管外皮细胞瘤占所有颅内肿瘤的比例不到1%。典型情况下,其行为具有侵袭性,表现出明显的局部或沿神经轴远处复发以及出现神经外转移的倾向。我们描述了一名74岁的患者,该患者出现非特异性症状,体格检查发现一个与皮肤粘连的无痛性耳后肿块。神经影像学研究显示后颅窝有一个大肿瘤,注入造影剂后有明显强化,导致枕骨-乳突显著骨质溶解,且仅由颈外动脉分支供血。患者接受了肿瘤全切术,在组织学诊断为血管外皮细胞瘤得到证实后,接受了初始辅助放疗。手术后16个月,患者无复发。颅内血管外皮细胞瘤的首选治疗方法是全切术,在技术可行时必须尝试,随后进行总剂量超过50 Gy的辅助放疗。这种联合治疗已证明可延长这些患者的无复发生存期。由于这些患者在最初适当治疗后数年甚至数十年可能出现复发或转移,因此必须进行密切和长期随访,以便早期诊断复发或转移。

相似文献

1
[Hemangiopericytoma of the posterior fossa: case report].[后颅窝血管外皮细胞瘤:病例报告]
Neurocirugia (Astur). 2008 Oct;19(5):446-52.
2
Intracranial meningeal hemangiopericytoma: the role of radiotherapy: report of 29 cases and review of the literature.颅内脑膜血管外皮细胞瘤:放射治疗的作用:29例报告及文献复习
Cancer. 2004 Apr 1;100(7):1491-7. doi: 10.1002/cncr.20109.
3
Hemangiopericytoma: Radical resection remains the cornerstone of therapy.血管外皮细胞瘤:根治性切除术仍是治疗的基石。
J Clin Neurosci. 2014 Apr;21(4):612-5. doi: 10.1016/j.jocn.2013.08.006. Epub 2013 Aug 27.
4
[Dorsal osseous hemangiopericytoma: a primary or metastatic tumour?].
Rev Neurol. 2009;48(12):636-8.
5
Hemangiopericytoma in the central nervous system. A study of eight cases.中枢神经系统血管外皮细胞瘤。八例研究。
Neurochirurgie. 2008 Feb;54(1):15-20. doi: 10.1016/j.neuchi.2007.12.003. Epub 2008 Mar 4.
6
Radiation-induced rhabdomyosarcomatous transformation of a recurrent meningeal haemangiopericytoma.
Acta Neurochir (Wien). 2007 Nov;149(11):1163-7; discussion 1167. doi: 10.1007/s00701-007-1289-8. Epub 2007 Oct 1.
7
Intracranial hemangiopericytoma: treatment outcomes in a consecutive series.颅内血管外皮细胞瘤:连续病例系列的治疗结果
Zentralbl Neurochir. 2007 Aug;68(3):111-8. doi: 10.1055/s-2007-981674. Epub 2007 Jul 30.
8
Surgical resection and adjuvant radiotherapy for a large pineal hemangiopericytoma.手术切除联合辅助放疗治疗巨大松果体血管外皮细胞瘤。
J Clin Neurosci. 2010 Sep;17(9):1209-11. doi: 10.1016/j.jocn.2010.01.022. Epub 2010 Jul 2.
9
Hemangiopericytoma/Solitary fibrous tumor of the oral cavity.口腔血管外皮细胞瘤/孤立性纤维瘤。
Anticancer Res. 2011 Feb;31(2):719-23.
10
Lipomatous hemangiopericytoma of the skull base and parapharyngeal space.颅底及咽旁间隙脂肪性血管外皮细胞瘤
Otol Neurotol. 2006 Jun;27(4):560-3. doi: 10.1097/01.mao.0000185152.46833.ab.

引用本文的文献

1
Combined Surgical Approach to Intracranial and Extracranial Hemangiopericytoma: Case Report and Literature Review.颅内和颅外血管外皮细胞瘤的联合手术方法:病例报告及文献综述
Cureus. 2020 Mar 28;12(3):e7447. doi: 10.7759/cureus.7447.