Fivaz B H, Rencken I, Cross R, Terry S, Hendry D
Department of Zoology and Entomology, Rhodes University, Grahamstown, South Africa.
Exp Appl Acarol. 1991 Jun;11(2-3):223-32. doi: 10.1007/BF01246094.
Repeated infestations of the rabbit with adult Rhipicephalus zambeziensis ticks resulted in a ten-fold reduction in engorgement weight of adult ticks and a significant decline in engorgement weight of nymphs. There was no evidence of cross-resistance against the South African bont tick, Amblyomma hebraeum. Immunization of rabbits with crude extracts of whole-tick protein significantly influenced engorgement weights and oviposition rates of adult R. zambeziensis. Histological studies of tissues from R. zambeziensis adults fed on resistant rabbits showed severe gut damage; this was associated with the binding of host IgG to mid-gut cells.
用成年赞比西河璃眼蜱反复感染兔子，导致成年蜱的饱血体重降低了十倍，若虫的饱血体重也显著下降。没有证据表明对南非褐色蜱（希伯来花蜱）存在交叉抗性。用蜱全蛋白粗提物对兔子进行免疫，显著影响了成年赞比西河璃眼蜱的饱血体重和产卵率。对取食抗性兔子的成年赞比西河璃眼蜱的组织进行组织学研究，发现肠道严重受损；这与宿主IgG与中肠细胞的结合有关。
