Eng-Ceceña Luis
Hospital Cardiológico, Los Mochis, Sin.
Arch Cardiol Mex. 2007 Oct-Dec;77 Suppl 4:S4-94-105.
Heart failure is a complex disorder involving maladaptive responses that result in defective regulation and function of multiple biological systems. Adequate understanding of these processes is basic for the development of novel therapeutic approaches. This review, directed to the molecular biology of the heart, is divided in three sections, with some redundancy between them: hypertrophy and remodeling, molecular composition of the failing heart, and molecular mechanisms leading to heart failure.
心力衰竭是一种复杂的病症，涉及适应性不良反应，导致多个生物系统的调节和功能出现缺陷。充分了解这些过程是开发新型治疗方法的基础。本综述针对心脏分子生物学，分为三个部分，各部分之间存在一些重叠：肥大与重塑、衰竭心脏的分子组成以及导致心力衰竭的分子机制。
