鸟类耳蜗中的毛细胞再生：如果它在鸟类中起作用，为什么在人类中不行呢？

Hair cell regeneration in the avian cochlea: if it works in birds, why not in man?

作者信息

Girod D A, Rubel E W

机构信息

Department of Otolaryngology, Head and Neck Surgery, University of Washington, Seattle 98195.

出版信息

Ear Nose Throat J. 1991 Jun;70(6):343-50, 353-4.

PMID:1893882

Abstract

Hearing loss caused by cochlear hair cell loss is the most common process afflicting the hearing impaired. Recent studies in the avian cochlea following ototoxic drug and noise damage have demonstrated a remarkable capacity for anatomical and functional recovery. Hair cell regeneration has been shown to play a major role in this recovery process. Future studies may one day make hair cell regeneration or transplantation possible in man.

摘要

由耳蜗毛细胞丧失引起的听力损失是困扰听力受损者的最常见过程。最近针对鸟类耳蜗在耳毒性药物和噪声损伤后的研究表明，其具有显著的解剖学和功能恢复能力。毛细胞再生已被证明在这一恢复过程中起主要作用。未来的研究也许有一天能使人类实现毛细胞再生或移植。