Falini Andrea, Romano Andrea, Bozzao Alessandro
Neuroradiology Unit and CERMAC Scientific Institute and University San Raffaele, Via Olgettina 60, 20132 Milan, Italy.
Neurol Sci. 2008 Oct;29 Suppl 3:327-32. doi: 10.1007/s10072-008-1009-z.
Detection of a brain lesion is the first diagnostic step in patients with symptoms and signs suggesting the presence of a brain tumour. Imaging is primarily done to prove or rule out the presence of such a lesion. The first diagnostic evaluation is based on neuroradiological imaging, and when the diagnosis of brain tumour is highly suspicious, the type of tumour should be characterized along with its grade of malignancy, as morphological imaging alone in not specific enough to give full comprehension of brain lesions. In recent years, after continuous developments in MRI, neuroimaging has evolved into a comprehensive diagnostic tool that allows the characterization of morphological and biological alterations to diagnose and grade brain tumours and to monitor and assess treatment response and patient prognosis.
对于出现提示脑肿瘤存在的症状和体征的患者,检测脑部病变是首要的诊断步骤。影像学检查主要用于证实或排除此类病变的存在。首次诊断评估基于神经放射学成像,当脑肿瘤的诊断高度可疑时,应确定肿瘤的类型及其恶性程度,因为仅靠形态学成像不足以全面了解脑部病变。近年来,随着磁共振成像(MRI)的不断发展,神经影像学已发展成为一种综合诊断工具,能够对形态学和生物学改变进行特征描述,以诊断脑肿瘤并对其进行分级,监测和评估治疗反应及患者预后。