Holman B L, Davis M A, Hanson R N
Semin Nucl Med. 1977 Jan;7(1):29-35. doi: 10.1016/s0001-2998(77)80005-6.
Detection of acute myocardial infarction as an area of increased activity has intrigued investigators for some time. Initial attempts with 203Hg-chlormerodrin and 203Hg-fluorescein analogues were successful in man. More recently, however, successful imaging of the acute myocardial infarct has been achieved with several 99mTc complexes. A large group of radiotracers localize in acutely damaged tissue in various models of experimental infarction. From these data, a number of specific structural properties associated with infarct avidity have been identified; these include the presence of mercury and the structural configuration of the organic carrier.
将急性心肌梗死检测为活性增加区域已经吸引了研究人员一段时间。最初使用203汞氯汞丙脲和203汞荧光素类似物的尝试在人体中取得了成功。然而，最近，使用几种99m锝复合物成功实现了急性心肌梗死的成像。一大类放射性示踪剂在各种实验性梗死模型的急性受损组织中定位。从这些数据中，已经确定了一些与梗死亲和力相关的特定结构特性；这些特性包括汞的存在和有机载体的结构构型。
