Sylvain-Moore H, Worden J P
Coronary Care Unit, Pitt County Memorial Hospital, Greenville, NC.
Heart Lung. 1991 Sep;20(5 Pt 1):464-6.
Lovastatin is a new drug that has become popular for the treatment of patients with hyperlipidemias. Rhabdomyolysis is a well-documented and potentially dangerous side effect of lovastatin therapy. Critical care nurses should be aware of the symptoms and treatment of rhabdomyolysis. Patients receiving lovastatin should be instructed to report muscle pain or weakness and dark urine immediately. It should be determined whether patients are at risk for development of rhabdomyolysis from other causes so that lovastatin can be withheld. Early diagnosis and treatment can prevent serious complications in patients with lovastatin-induced rhabdomyolysis.
洛伐他汀是一种新型药物，已广泛用于治疗高脂血症患者。横纹肌溶解是洛伐他汀治疗中一种有充分文献记载且潜在危险的副作用。重症监护护士应了解横纹肌溶解的症状及治疗方法。接受洛伐他汀治疗的患者应被告知立即报告肌肉疼痛或无力以及深色尿液。应确定患者是否因其他原因有发生横纹肌溶解的风险，以便停用洛伐他汀。早期诊断和治疗可预防洛伐他汀诱导的横纹肌溶解患者出现严重并发症。
