Zou Li-Xia, Gong Fang-Qi
Department of Internal Medicine, Children's Hospital Affiliated to School of Medicine of Zhejiang University, Hangzhou 310003, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2008 Oct;10(5):617-9.
To investigate the clinical features of recurrent Kawasaki disease (KD) and the relationship of recurrent KD with coronary artery lesions.
The medical data of 20 children with recurrent KD who were admitted to the Children's Hospital from January 1998 to May 2007 were retrospectively studied. Their clinical features were compared with those of children with initial KD.
The incidence of recurrent KD was 1.34% (20/1489). KD relapsed 2 months to 4.6 years (average: 1.2 years) after the first episode in the 20 children. Compared with the initial KD group, the clinical symptoms in the recurrent KD group were incomplete, complicated and less severe. The period of fever, platelet count, C-reactive protein and ESR were remarkably reduced in the recurrent KD group, but the incidence of coronary artery lesions increased significantly compared with the initial KD group (40% vs 25%; P<0.05).
The clinical symptoms of recurrent KD were incomplete in children. Recurrent KD was associated with an increased incidence of coronary artery lesions.
探讨复发性川崎病（KD）的临床特征以及复发性KD与冠状动脉病变的关系。
回顾性研究1998年1月至2007年5月在儿童医院收治的20例复发性KD患儿的医疗资料。将其临床特征与初发性KD患儿的临床特征进行比较。
复发性KD的发生率为1.34%（20/1489）。20例患儿在首次发病后2个月至4.6年（平均1.2年）复发KD。与初发性KD组相比，复发性KD组的临床症状不典型、复杂且较轻。复发性KD组的发热时间、血小板计数、C反应蛋白和血沉显著降低，但与初发性KD组相比，冠状动脉病变的发生率显著增加（40%对25%；P<0.05）。
儿童复发性KD的临床症状不典型。复发性KD与冠状动脉病变发生率增加有关。
