Burgu Berk, Duffy Patrick G, Cuckow Peter, Ransley Philip, Wilcox Duncan T
Great Ormond Street Children's Hospital NHS Trust and Guys Hospital, London, UK.
J Pediatr Urol. 2007 Aug;3(4):316-20. doi: 10.1016/j.jpurol.2006.09.008. Epub 2006 Dec 22.
In a retrospective review, to analyse the long-term outcomes of vaginal reconstruction, comparing techniques and timing.
We identified 63 patients who underwent a total of 71 vaginoplasties in 1985-2000. The techniques used were posterior skin flap (42), intestinal replacement (21) and pull through (8). The majority of operations were performed before puberty (63%) and as primary procedures (79%). Presenting diagnoses were congenital adrenal hyperplasia (23), cloacal exstrophy (8), true persistent cloaca (12), androgen insensitivity (8), urogenital sinus anomaly (6), mixed gonadal dysgenesis (3), true hermaphroditism (2) and sacrococcygeal teratoma (1).
The mean age at operation was 83.9 (2-235) and mean follow up was 116.8 (48-232) months. Strictures and discharge were the most common problems. Nine patients underwent revision surgery and a fistula repair was required in two patients. Mucosal prolapse was observed in one ileo- and one colovaginoplasty patient, and diversion colitis occurred after colovaginoplasty in one patient. More complications occurred in operations performed prior to than following puberty.
If vaginoplasty is the only indicated operation, delaying until puberty may minimize complications. When other genital surgery is indicated or in the presence of symptoms pre-pubertal vaginoplasty should be performed, since the second procedure usually involves simple dilatations and is associated with good results.
在一项回顾性研究中,分析阴道重建的长期效果,比较不同技术及手术时机。
我们确定了63例患者,他们在1985年至2000年间共接受了71次阴道成形术。所采用的技术包括后皮瓣法(42例)、肠代阴道术(21例)和拖出术(8例)。大多数手术在青春期前进行(63%),且为一期手术(79%)。主要诊断包括先天性肾上腺皮质增生症(23例)、泄殖腔外翻(8例)、真性永存泄殖腔(12例)、雄激素不敏感综合征(8例)、泌尿生殖窦畸形(6例)、混合性性腺发育不全(3例)、真两性畸形(2例)和骶尾部畸胎瘤(1例)。
手术时的平均年龄为83.9(2 - 235)个月,平均随访时间为116.8(48 - 232)个月。狭窄和分泌物增多是最常见的问题。9例患者接受了修复手术,2例患者需要进行瘘管修复。1例回肠阴道成形术和1例结肠阴道成形术患者出现黏膜脱垂,1例结肠阴道成形术患者术后发生了改道性结肠炎。青春期前进行的手术比青春期后进行的手术出现更多并发症。
如果阴道成形术是唯一需要进行的手术,推迟到青春期进行可能会使并发症最少。当需要进行其他生殖器手术或存在青春期前症状时,应进行阴道成形术,因为二次手术通常只需简单扩张,且效果良好。