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先天性肾上腺皮质增生症和阴蒂肥大患儿行阴蒂成形术的手术效果:单外科医生 19 年经验。

Surgical Outcomes of Clitoroplasty in Children with Congenital Adrenal Hyperplasia and Clitoral Hypertrophy: A 19-Year Experience of a Single Surgeon.

机构信息

Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05535, Korea.

Department of Urology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 44033, Korea.

出版信息

Int J Environ Res Public Health. 2021 Oct 23;18(21):11152. doi: 10.3390/ijerph182111152.

Abstract

This study aimed to describe the experience with clitoroplasty for clitoral hypertrophy in patients with congenital adrenal hyperplasia of a single surgeon. The medical records of female pediatric patients with congenital adrenal hyperplasia who underwent clitoroplasty at a tertiary referral hospital between 2002 and 2020 were retrospectively analyzed. Three different surgical techniques were applied for clitoroplasty: recession without reduction, reduction and recession, and girth reduction and recession. A total of 104 patients underwent clitoroplasty for clitoral hypertrophy. The median patient age at the time of surgery was 10 months (range, 4 months to 10 years). The operation time was longer in reduction clitoroplasty than in recession clitoroplasty without reduction (median, 153 vs. 111 min, = 0.003). The mean postoperative pain score of the patients did not differ among the different clitoroplasty techniques. During the mean follow-up of 37.7 months, nine (8.6%) patients underwent reperformed clitoroplasty. The rate of reperformed operation was significantly higher in patients who underwent reduction clitoroplasty (17.3%) than in those who underwent recession without reduction (2%) or girth reduction and recession (0%) ( = 0.031). Early clitoroplasty in patients with congenital adrenal hyperplasia yielded good mid-term surgical outcomes in terms of cosmesis and recurrence rate, with minimal perioperative complications.

摘要

本研究旨在描述单外科医生在先天性肾上腺皮质增生症患者中进行阴蒂整形术的经验。回顾性分析了 2002 年至 2020 年期间在一家三级转诊医院接受阴蒂整形术的先天性肾上腺皮质增生症女性儿科患者的病历。阴蒂整形术采用了三种不同的手术技术:不减少的退缩术、减少和退缩术以及周长减少和退缩术。共有 104 例患者因阴蒂肥大而行阴蒂整形术。手术时患者的中位年龄为 10 个月(范围为 4 个月至 10 岁)。减少的阴蒂整形术的手术时间长于不减少的退缩术(中位数,153 与 111 分钟, = 0.003)。不同阴蒂整形术技术的患者术后平均疼痛评分无差异。在平均 37.7 个月的随访期间,有 9 名(8.6%)患者再次行阴蒂整形术。接受减少的阴蒂整形术的患者中再次手术的比例(17.3%)明显高于不减少退缩术(2%)或周长减少和退缩术(0%)( = 0.031)。先天性肾上腺皮质增生症患者早期行阴蒂整形术,中期美容效果和复发率较好,围手术期并发症少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4709/8583494/da0f5e151704/ijerph-18-11152-g001.jpg

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