Emmiler Mustafa, Solak Ozlem, Kocogullari Cevdet, Dundar Umit, Ayva Ercument, Ela Yuksel, Cekirdekci Ahmet, Kavuncu Vural
Department of Cardiovascular Surgery, Afyon Kocatepe University, School of Medicine, Afyon, Turkey.
Heart Surg Forum. 2008;11(5):E300-3. doi: 10.1532/HSF98.20081083.
We investigated the effectiveness of transcutaneous electrical nerve stimulation (TENS) therapy on pain during the first 24 hours after a cardiac surgical procedure.
A total of 60 patients who had undergone median sternotomy (MS) for coronary artery bypass graft (n = 55) or valve repair surgery (n = 5) were randomized to receive TENS and pharmacologic analgesia, placebo TENS and pharmacologic analgesia, or pharmacologic analgesia alone (control group). For each group we recorded severity of pain, analgesic intake, and pulmonary complications. Pethidine HCL and metamizol sodium were administered for postsurgical analgesia.
Pain after MS was measured on a 10-point visual analogue scale (VAS). Mean scores in the TENS, placebo TENS, and control groups, respectively, were 5.70 +/- 1.78, 5.75 +/- 1.83, and 5.95 +/- 1.63 before treatment (P >.05); 2.40 +/- 1.18, 3.90 +/- 1.48, and 3.55 +/- 1.60 on the 12th hour of the intervention (P < .05); and 1.25 +/- 0.91, 2.30 +/- 1.34, and 2.15 +/- 1.13 on the 24th hour of the intervention (P < .05). The mean VAS scores decreased within each group (P < .05). However, the mean VAS scores decreased much more significantly in the TENS group (P < .05). Metamizol sodium intake was 1.05 +/- 0.39 g, 2.30 +/- 1.08 g, and 2.90 +/- 1.20 g and pethidine HCL intake was 17 +/- 16.25 mg, 57 +/- 21.54 mg, and 51.50 +/- 18.99 mg, respectively, in the TENS, placebo TENS, and control groups. Metamizol sodium and pethidine HCL intake was least in the TENS group (P < .05). Postoperative complications were observed in 6 (10%) of patients. The most frequent complication was atelectasia.
TENS was more effective than placebo TENS or control treatments in decreasing pain and limiting opioid and nonopioid medication intake during the first 24-hour period following MS.
我们研究了经皮电刺激神经疗法(TENS)对心脏外科手术后最初24小时内疼痛的疗效。
共有60例接受正中胸骨切开术(MS)进行冠状动脉搭桥术(n = 55)或瓣膜修复手术(n = 5)的患者被随机分为三组,分别接受TENS与药物镇痛、安慰剂TENS与药物镇痛或单纯药物镇痛(对照组)。我们记录了每组患者的疼痛严重程度、镇痛药物摄入量和肺部并发症情况。使用盐酸哌替啶和安乃近进行术后镇痛。
MS术后疼痛采用10分视觉模拟量表(VAS)进行测量。治疗前,TENS组、安慰剂TENS组和对照组的平均得分分别为5.70±1.78、5.75±1.83和5.95±1.63(P>.05);干预第12小时分别为2.40±1.18、3.90±1.48和3.55±1.60(P<.05);干预第24小时分别为1.25±0.91、2.30±1.34和2.15±1.13(P<.05)。每组内平均VAS得分均下降(P<.05)。然而,TENS组平均VAS得分下降更为显著(P<.05)。TENS组、安慰剂TENS组和对照组的安乃近摄入量分别为1.05±0.39 g、2.30±1.08 g和2.90±1.20 g,盐酸哌替啶摄入量分别为17±16.25 mg、57±21.54 mg和51.50±18.99 mg。TENS组的安乃近和盐酸哌替啶摄入量最少(P<.05)。6例(10%)患者出现术后并发症。最常见的并发症是肺不张。
在MS术后的最初24小时内,TENS在减轻疼痛以及限制阿片类和非阿片类药物摄入量方面比安慰剂TENS或对照治疗更有效。