Chhabra Darshika, Nash Kevin
Evanston Northwestern Healthcare, Feinberg School of Medicine, Division of Nephrology and Hypertension, Chicago, Illinois, Il 60201, Evanston, USA.
Expert Opin Drug Metab Toxicol. 2008 Nov;4(11):1455-64. doi: 10.1517/17425255.4.11.1455.
Peritoneal dialysis is a home dialysis therapy in which a fluid known as dialysate is placed into the patient's peritoneal cavity. The standard dialysate consists of a concentrated dextrose solution. Icodextrin is a glucose polymer that can be substituted for dextrose with avoidance of some of the glucose-dependant effects. The efficacy and safety of this compound was evaluated and compared with the standard dialysate solutions. It seems to be well-tolerated overall and may offer benefits in select populations of patients with kidney failure. This seems to be especially relevant in patients with more permeable peritoneal membranes who are known as 'high-transporters'.
腹膜透析是一种家庭透析疗法，即把一种称为透析液的液体注入患者的腹腔。标准透析液由浓缩葡萄糖溶液组成。艾考糊精是一种葡萄糖聚合物，可替代葡萄糖，避免一些与葡萄糖相关的影响。对该化合物的疗效和安全性进行了评估，并与标准透析液进行了比较。总体而言，它似乎耐受性良好，可能对某些肾衰竭患者群体有益。这在腹膜通透性较高的患者（即所谓的“高转运者”）中似乎尤为相关。
