Dept. of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, Ioannina, Greece.
Diagn Pathol. 2008 Oct 24;3:42. doi: 10.1186/1746-1596-3-42.
Male breast cancer is rare compared to its female counterpart representing less than 1% of cancer in men. Moreover, mucinous carcinoma of the male breast is an extremely rare histological subtype of malignancy. Paget's disease of the nipple is rarely observed in males.
Herein, we describe a unique case of an 86 years old man with mucinous breast cancer presenting as Paget's disease of the nipple. According to the immunohistochemical evaluation the neoplastic cells were positive for estrogen (ER) and progesterone receptors (PR).
To our best knowledge this is the first case of mucinous male breast cancer presenting as Paget's disease of the nipple.
与女性乳腺癌相比,男性乳腺癌较为罕见,占男性癌症的比例不足 1%。此外,男性乳腺的黏液癌是一种极为罕见的恶性组织学亚型。男性中很少观察到乳头 Paget 病。
本文描述了一例罕见的 86 岁男性病例,其患有黏液性乳腺癌,表现为乳头 Paget 病。根据免疫组织化学评估,肿瘤细胞对雌激素受体 (ER) 和孕激素受体 (PR) 呈阳性。
据我们所知,这是首例表现为乳头 Paget 病的男性黏液性乳腺癌病例。