Sadiq M, Islam K, Abid R, Latif F, Rehman A U, Waheed A, Azhar M, Khan J S
Department of Paediatric Cardiology, Punjab Institute of Cardiology, Lahore, Pakistan.
Heart. 2009 Mar;95(5):353-7. doi: 10.1136/hrt.2008.143982. Epub 2008 Oct 24.
To determine the prevalence of rheumatic heart disease (RHD) among school children in urban and semiurban areas of Lahore, Pakistan.
A cross-sectional survey of school children aged 5-15 years from 70 schools of urban and semiurban Lahore was carried out by a team of cardiologists. Children were screened by clinical examination and diagnosis confirmed by echocardiography. Sociodemographic data were also collected.
Of 24 980 children screened, 986 (3.9%) had a confirmed cardiac lesion; 546 had RHD, 440 had congenital heart disease. The prevalence of RHD was 21.9/1000 children screened (95% CI 20.1 to 23.7). Their mean (SD) age was 10.7 (2.6) years and the female:male ratio was 1.6:1. Most (92.5%) were unaware of the diagnosis and less than 2% were taking rheumatic prophylaxis. All children belonged to a low socioeconomic group and 67% were undernourished.
The prevalence of RHD in the urban school population of Lahore is among the highest in the world. The younger age of onset is a special feature and most are unaware of the diagnosis, and hence not receiving life-saving secondary prophylaxis.
确定巴基斯坦拉合尔市区和半市区学龄儿童风湿性心脏病(RHD)的患病率。
一组心脏病专家对拉合尔市区和半市区70所学校5至15岁的学龄儿童进行了横断面调查。通过临床检查对儿童进行筛查,并通过超声心动图确诊。还收集了社会人口统计学数据。
在筛查的24980名儿童中,986名(3.9%)确诊有心脏病变;546名患有风湿性心脏病,440名患有先天性心脏病。筛查儿童中风湿性心脏病的患病率为21.9/1000(95%可信区间20.1至23.7)。他们的平均(标准差)年龄为10.7(2.6)岁,女性与男性比例为1.6:1。大多数(92.5%)不知道自己的诊断情况,不到2%的人正在接受风湿热预防治疗。所有儿童都属于社会经济地位较低的群体,67%的儿童营养不良。
拉合尔市区学校人群中风湿性心脏病的患病率位居世界前列。发病年龄较小是一个特殊特征,大多数人不知道自己的诊断情况,因此没有接受挽救生命的二级预防治疗。