Lo Helen G, Matheny Michael E, Seger Diane L, Bates David W, Gandhi Tejal K
Department of Emergency Medicine, Hospital of University of Pennsylvania, Philadelphia, PA, USA.
J Am Med Inform Assoc. 2009 Jan-Feb;16(1):66-71. doi: 10.1197/jamia.M2687. Epub 2008 Oct 24.
Interruptive alerts within electronic applications can cause "alert fatigue" if they fire too frequently or are clinically reasonable only some of the time. We assessed the impact of non-interruptive, real-time medication laboratory alerts on provider lab test ordering.
We enrolled 22 outpatient practices into a prospective, randomized, controlled trial. Clinics either used the existing system or received on-screen recommendations for baseline laboratory tests when prescribing new medications. Since the warnings were non-interruptive, providers did not have to act upon or acknowledge the notification to complete a medication request.
Data were collected each time providers performed suggested laboratory testing within 14 days of a new prescription order. Findings were adjusted for patient and provider characteristics as well as patient clustering within clinics.
Among 12 clinics with 191 providers in the control group and 10 clinics with 175 providers in the intervention group, there were 3673 total events where baseline lab tests would have been advised: 1988 events in the control group and 1685 in the intervention group. In the control group, baseline labs were requested for 771 (39%) of the medications. In the intervention group, baseline labs were ordered by clinicians in 689 (41%) of the cases. Overall, no significant association existed between the intervention and the rate of ordering appropriate baseline laboratory tests.
We found that non-interruptive medication laboratory monitoring alerts were not effective in improving receipt of recommended baseline laboratory test monitoring for medications. Further work is necessary to optimize compliance with non-critical recommendations.
如果电子应用程序中的中断性警报触发过于频繁,或者只是在某些时候具有临床合理性,那么这些警报可能会导致“警报疲劳”。我们评估了非中断性实时用药实验室警报对医疗服务提供者实验室检查医嘱的影响。
我们招募了22个门诊机构参与一项前瞻性随机对照试验。各诊所要么使用现有系统,要么在开具新药物处方时接收关于基线实验室检查的屏幕提示。由于这些警告是非中断性的,医疗服务提供者无需对通知采取行动或确认即可完成用药申请。
每次医疗服务提供者在新处方开具后的14天内进行建议的实验室检查时,我们都会收集数据。研究结果针对患者和医疗服务提供者的特征以及诊所内患者的聚类情况进行了调整。
在对照组的12个诊所(共191名医疗服务提供者)和干预组的10个诊所(共175名医疗服务提供者)中,总共发生了3673起建议进行基线实验室检查的事件:对照组1988起,干预组1685起。在对照组中,771种(39%)药物被要求进行基线实验室检查。在干预组中,临床医生在689例(41%)病例中开具了基线实验室检查医嘱。总体而言,干预措施与适当进行基线实验室检查的医嘱率之间不存在显著关联。
我们发现,非中断性用药实验室监测警报在改善对推荐的用药基线实验室检查监测的接受情况方面并不有效。有必要进一步开展工作,以优化对非关键建议的依从性。