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本文引用的文献

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A randomized trial of electronic clinical reminders to improve medication laboratory monitoring.一项关于电子临床提醒以改善药物实验室监测的随机试验。
J Am Med Inform Assoc. 2008 Jul-Aug;15(4):424-9. doi: 10.1197/jamia.M2602. Epub 2008 Apr 24.
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Developments in cluster randomized trials and Statistics in Medicine.整群随机试验的进展与《医学统计学》
Stat Med. 2007 Jan 15;26(1):2-19. doi: 10.1002/sim.2731.
3
Medication-related clinical decision support in computerized provider order entry systems: a review.计算机化医嘱录入系统中与药物治疗相关的临床决策支持:综述
J Am Med Inform Assoc. 2007 Jan-Feb;14(1):29-40. doi: 10.1197/jamia.M2170. Epub 2006 Oct 26.
4
A pragmatic approach to implementing best practices for clinical decision support systems in computerized provider order entry systems.一种在计算机化医嘱录入系统中实施临床决策支持系统最佳实践的实用方法。
J Am Med Inform Assoc. 2007 Jan-Feb;14(1):25-8. doi: 10.1197/jamia.M2173. Epub 2006 Oct 26.
5
Which drugs cause preventable admissions to hospital? A systematic review.哪些药物会导致可避免的住院情况?一项系统评价。
Br J Clin Pharmacol. 2007 Feb;63(2):136-47. doi: 10.1111/j.1365-2125.2006.02698.x. Epub 2006 Jun 26.
6
Prescribers' responses to alerts during medication ordering in the long term care setting.长期护理机构中开处方者对用药医嘱提醒的反应。
J Am Med Inform Assoc. 2006 Jul-Aug;13(4):385-90. doi: 10.1197/jamia.M1945. Epub 2006 Apr 18.
7
Laboratory monitoring of drugs at initiation of therapy in ambulatory care.门诊治疗开始时药物的实验室监测。
J Gen Intern Med. 2005 Dec;20(12):1120-6. doi: 10.1111/j.1525-1497.2005.0257.x.
8
Overriding of drug safety alerts in computerized physician order entry.计算机化医生医嘱录入系统中药物安全警报的忽略
J Am Med Inform Assoc. 2006 Mar-Apr;13(2):138-47. doi: 10.1197/jamia.M1809. Epub 2005 Dec 15.
9
The anatomy of decision support during inpatient care provider order entry (CPOE): empirical observations from a decade of CPOE experience at Vanderbilt.住院护理人员医嘱录入(CPOE)过程中的决策支持剖析:来自范德比尔特十年CPOE经验的实证观察
J Biomed Inform. 2005 Dec;38(6):469-85. doi: 10.1016/j.jbi.2005.08.009. Epub 2005 Oct 21.
10
Improving laboratory monitoring at initiation of drug therapy in ambulatory care: a randomized trial.改善门诊护理中药物治疗起始时的实验室监测:一项随机试验。
Arch Intern Med. 2005 Nov 14;165(20):2395-401. doi: 10.1001/archinte.165.20.2395.

门诊护理中无干扰药物实验室监测警报的影响

Impact of non-interruptive medication laboratory monitoring alerts in ambulatory care.

作者信息

Lo Helen G, Matheny Michael E, Seger Diane L, Bates David W, Gandhi Tejal K

机构信息

Department of Emergency Medicine, Hospital of University of Pennsylvania, Philadelphia, PA, USA.

出版信息

J Am Med Inform Assoc. 2009 Jan-Feb;16(1):66-71. doi: 10.1197/jamia.M2687. Epub 2008 Oct 24.

DOI:10.1197/jamia.M2687
PMID:18952945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2605597/
Abstract

OBJECTIVE

Interruptive alerts within electronic applications can cause "alert fatigue" if they fire too frequently or are clinically reasonable only some of the time. We assessed the impact of non-interruptive, real-time medication laboratory alerts on provider lab test ordering.

DESIGN

We enrolled 22 outpatient practices into a prospective, randomized, controlled trial. Clinics either used the existing system or received on-screen recommendations for baseline laboratory tests when prescribing new medications. Since the warnings were non-interruptive, providers did not have to act upon or acknowledge the notification to complete a medication request.

MEASUREMENTS

Data were collected each time providers performed suggested laboratory testing within 14 days of a new prescription order. Findings were adjusted for patient and provider characteristics as well as patient clustering within clinics.

RESULTS

Among 12 clinics with 191 providers in the control group and 10 clinics with 175 providers in the intervention group, there were 3673 total events where baseline lab tests would have been advised: 1988 events in the control group and 1685 in the intervention group. In the control group, baseline labs were requested for 771 (39%) of the medications. In the intervention group, baseline labs were ordered by clinicians in 689 (41%) of the cases. Overall, no significant association existed between the intervention and the rate of ordering appropriate baseline laboratory tests.

CONCLUSION

We found that non-interruptive medication laboratory monitoring alerts were not effective in improving receipt of recommended baseline laboratory test monitoring for medications. Further work is necessary to optimize compliance with non-critical recommendations.

摘要

目的

如果电子应用程序中的中断性警报触发过于频繁,或者只是在某些时候具有临床合理性,那么这些警报可能会导致“警报疲劳”。我们评估了非中断性实时用药实验室警报对医疗服务提供者实验室检查医嘱的影响。

设计

我们招募了22个门诊机构参与一项前瞻性随机对照试验。各诊所要么使用现有系统,要么在开具新药物处方时接收关于基线实验室检查的屏幕提示。由于这些警告是非中断性的,医疗服务提供者无需对通知采取行动或确认即可完成用药申请。

测量

每次医疗服务提供者在新处方开具后的14天内进行建议的实验室检查时,我们都会收集数据。研究结果针对患者和医疗服务提供者的特征以及诊所内患者的聚类情况进行了调整。

结果

在对照组的12个诊所(共191名医疗服务提供者)和干预组的10个诊所(共175名医疗服务提供者)中,总共发生了3673起建议进行基线实验室检查的事件:对照组1988起,干预组1685起。在对照组中,771种(39%)药物被要求进行基线实验室检查。在干预组中,临床医生在689例(41%)病例中开具了基线实验室检查医嘱。总体而言,干预措施与适当进行基线实验室检查的医嘱率之间不存在显著关联。

结论

我们发现,非中断性用药实验室监测警报在改善对推荐的用药基线实验室检查监测的接受情况方面并不有效。有必要进一步开展工作,以优化对非关键建议的依从性。