Lamont Leigh A
Department of Companion Animals, Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island, Canada C1A 4P3.
Vet Clin North Am Small Anim Pract. 2008 Nov;38(6):1187-203, v. doi: 10.1016/j.cvsm.2008.06.002.
Adjunctive analgesic therapies are interventions for pain that involve agents or techniques other than the traditional analgesics (opioids, nonsteroidal anti-inflammatory drugs, and local anesthetics). Adjunctive therapies may be pharmacologic or nonpharmacologic in nature. The focus of this article is on pharmacologic interventions with potential utility as adjunctive analgesics in veterinary medicine. Pharmacology of selected agents, including medetomidine, ketamine, amantadine, gabapentin, systemic lidocaine, and pamidronate, is discussed in addition to evidence for their safety and efficacy and guidelines for their use in veterinary patients.
辅助镇痛疗法是针对疼痛的干预措施，涉及传统镇痛药（阿片类药物、非甾体抗炎药和局部麻醉药）以外的药物或技术。辅助疗法在性质上可能是药物性的或非药物性的。本文重点关注在兽医学中具有作为辅助镇痛药潜在效用的药物干预措施。除了所选药物（包括美托咪定、氯胺酮、金刚烷胺、加巴喷丁、全身性利多卡因和帕米膦酸盐）的安全性和有效性证据以及在兽医患者中使用的指南外，还讨论了这些药物的药理学。
