生物标志物：脓毒症的诊断与风险评估
Biomarkers: diagnosis and risk assessment in sepsis.
作者信息
Ventetuolo Corey E, Levy Mitchell M
机构信息
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, PH 8, Room 101, 622 W. 168th Street, New York City, NY 10032, USA.
出版信息
Clin Chest Med. 2008 Dec;29(4):591-603, vii. doi: 10.1016/j.ccm.2008.07.001.
Prompt diagnosis, intervention, and risk assessment are critical in caring for septic patient but remain difficult with currently available methods. Biomarkers may become useful adjuncts to clinicians and ultimately serve as targets for future therapeutic trials in sepsis. The most relevant markers are reviewed in this article, including interleukin-6, C-reactive protein, procalcitonin, triggering receptor expressed on myeloid cells-1, and biomarker panels.
快速诊断、干预和风险评估对于脓毒症患者的护理至关重要，但目前可用的方法仍难以做到。生物标志物可能成为临床医生有用的辅助手段，并最终成为未来脓毒症治疗试验的靶点。本文对最相关的标志物进行了综述，包括白细胞介素-6、C反应蛋白、降钙素原、髓系细胞表达的触发受体-1以及生物标志物组合。
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