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艾滋病患者鸟分枝杆菌复合群所致腹膜炎:5例报告及文献复习

Peritonitis due to Mycobacterium avium complex in patients with AIDS: report of five cases and review of the literature.

作者信息

Wu Un-In, Chen Mao-Yuan, Hu Ruey-Heng, Hsieh Szu-Min, Sheng Wang-Huei, Lo Yi-Chun, Hung Chien-Ching, Chang Shan-Chwen

机构信息

Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, 7 Chung-Shan South Road, Taipei 100, Taiwan.

出版信息

Int J Infect Dis. 2009 Mar;13(2):285-90. doi: 10.1016/j.ijid.2008.07.016. Epub 2008 Oct 26.

Abstract

BACKGROUND

Mycobacterium avium complex (MAC) often causes disseminated infection in patients at an advanced stage of HIV infection; however, peritonitis associated with disseminated MAC infection is rare.

METHODS

In this report, we describe five cases of MAC peritonitis in AIDS patients at our hospital, and analyze these cases alongside 11 previously published cases found in the literature.

RESULTS

Most of the AIDS patients with MAC peritonitis had CD4 counts of <50 cells/microl and elevated alkaline phosphatase levels. Other than ascites, MAC was also isolated from other sterile and non-sterile sites. Of note, six patients (37.5%) presented with chylous ascites.

CONCLUSIONS

Despite therapy, MAC peritonitis is associated with a grave outcome.

摘要

背景

鸟分枝杆菌复合体(MAC)常导致处于HIV感染晚期的患者发生播散性感染;然而,与播散性MAC感染相关的腹膜炎较为罕见。

方法

在本报告中,我们描述了我院5例艾滋病患者发生MAC腹膜炎的病例,并结合文献中11例先前发表的病例对这些病例进行分析。

结果

大多数患有MAC腹膜炎的艾滋病患者CD4细胞计数<50个/微升,碱性磷酸酶水平升高。除腹水外,MAC还从其他无菌和非无菌部位分离出来。值得注意的是,6例患者(37.5%)出现乳糜性腹水。

结论

尽管进行了治疗,MAC腹膜炎的预后仍很严重。

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