Chen Mei-Ju, Liu Jui-Ling, Li Wing-Yin, Lee Fenq-Lih, Chou Ching-Kuang, Hsu Wen-Ming
Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
J Chin Med Assoc. 2008 Oct;71(10):546-8. doi: 10.1016/S1726-4901(08)70166-7.
Iris melanocytoma is a rare melanocytic nevus with distinctive clinical and pathologic features. Secondary glaucoma may develop rapidly and respond poorly to glaucoma medication in some cases. However, few data are available in the literature with respect to the appropriate treatment for refractory glaucoma associated with iris melanocytoma. Herein, we present a 28-year-old man with blurred vision and an elevated intraocular pressure (IOP) of 40 mmHg in his right eye while on multiple glaucoma medications. A dark brown lobulated iris mass with surrounding small pigmented lesions was noted between the 4 and 5:30 o'clock positions. Sector iridectomy was performed and pathologic examination revealed an iris melanocytoma. After surgery, antiglaucomatous medications still failed to control IOP. The patient then underwent diode laser transscleral cyclophotocoagulation (TSCP). At the last follow-up of 15 months, IOP had returned to normal without the need for medication.
虹膜黑素细胞瘤是一种罕见的黑素细胞痣,具有独特的临床和病理特征。继发性青光眼可能迅速发展,在某些情况下对青光眼药物反应不佳。然而,关于与虹膜黑素细胞瘤相关的难治性青光眼的适当治疗,文献中几乎没有相关数据。在此,我们报告一名28岁男性,在使用多种青光眼药物治疗期间,右眼视力模糊,眼压升高至40 mmHg。在4点至5点30分位置之间可见一个深褐色分叶状虹膜肿物,周围有小的色素沉着病变。行扇形虹膜切除术,病理检查显示为虹膜黑素细胞瘤。手术后,抗青光眼药物仍无法控制眼压。该患者随后接受了二极管激光经巩膜睫状体光凝术(TSCP)。在最后一次随访的15个月时,眼压已恢复正常,无需药物治疗。