Wei Wei, Yu Xueqing, Yang Lu, Xiong Chan, Zhang Xu
Affiliated Eye Hospital of Nanchang University, Jiangxi Research Institute of Ophthalmology and Visual Science, Jiangxi Clinical Research Center of Ophthalmic Disease, Nanchang, Jiangxi, People's Republic of China.
BMC Ophthalmol. 2021 Jun 29;21(1):268. doi: 10.1186/s12886-021-02026-x.
With the rapid development of intraocular collamer lens (ICL) operation, it is foreseeable that we will encounter a large number of glaucoma patients with ICL implantation history. However, our current understanding of the treatment of glaucoma patients with ICL is limited. Hence we report a rare case of refractory glaucoma after intraocular collamer lens and intraocular lens implantation in a patient who underwent unsuccessful transscleral cyclophotocoagulation, which led to intraocular collamer lens displacement, angle closure and uncontrolled intraocular pressure.
A 39-year-old woman presented with intractably elevated intraocular pressure in the right eye. Since her intraocular collamer lens implantation surgery in 2017, her intraocular pressure had remained over 40 mmHg while using 3 types of anti-glaucoma medications. The patient had a history of phacoemulsification and posterior chamber phakic intraocular lens implantation for complicated cataracts secondary to uveitis in 2006. On gonioscope examination, there were signs of pigment dispersion, and the anterior chamber angle was open. Ultrasound biomicroscopy examination showed contact and rubbing between the intraocular collamer lens and posterior surface of the iris. And typical advanced glaucomatous optic neuropathy and visual field defects were observed. Transscleral cyclophotocoagulation was performed to control the intraocular pressure and prevent further visual field loss. However, the intraocular collamer lens was displaced after transscleral cyclophotocoagulation, which resulted in formation of a shallow anterior chamber 1 week later, angle closure and loss of intraocular pressure control 1 month later, even though the maximum dose of anti-glaucoma medication was used. Finally, an Ahmed glaucoma valve was successfully implanted in her anterior chamber, and the glaucoma was controlled, as observed at the 10-month follow-up.
Pigment dispersion is a common phenomenon after intraocular collamer lens implantation and may accelerate the progression of glaucoma. Transscleral cyclophotocoagulation should be carefully considered in glaucoma patients with elevated intraocular pressure after intraocular collamer lens implantation, given that transscleral cyclophotocoagulation may cause intraocular collamer lens displacement.
随着眼内可植入式接触镜(ICL)手术的迅速发展,可以预见,我们将会遇到大量有ICL植入史的青光眼患者。然而,我们目前对ICL植入后青光眼患者治疗的了解有限。因此,我们报告了1例在接受经巩膜睫状体光凝术失败后出现难治性青光眼的罕见病例,该患者在眼内植入了可植入式接触镜和人工晶状体,导致可植入式接触镜移位、房角关闭和眼压失控。
一名39岁女性因右眼眼压顽固升高前来就诊。自2017年接受眼内可植入式接触镜植入手术以来,在使用3种抗青光眼药物的情况下,她的眼压仍持续超过40 mmHg。该患者在2006年有过因葡萄膜炎继发复杂白内障而接受超声乳化白内障吸除术及后房型有晶状体眼人工晶状体植入术的病史。在房角镜检查中,有色素播散的迹象,前房角开放。超声生物显微镜检查显示眼内可植入式接触镜与虹膜后表面存在接触和摩擦。并且观察到典型的晚期青光眼性视神经病变和视野缺损。为控制眼压并防止视野进一步丧失,进行了经巩膜睫状体光凝术。然而,经巩膜睫状体光凝术后可植入式接触镜发生移位,1周后导致前房变浅,1个月后房角关闭且眼压控制不佳,尽管已使用最大剂量的抗青光眼药物。最后,在她的前房成功植入了艾哈迈德青光眼引流阀,青光眼得到控制,在10个月的随访中观察到这一情况。
色素播散是眼内可植入式接触镜植入术后的常见现象,可能会加速青光眼的进展。对于ICL植入术后眼压升高的青光眼患者,鉴于经巩膜睫状体光凝术可能导致可植入式接触镜移位,应谨慎考虑该治疗方法。