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肥厚型心肌病的体力活动耐量及其决定因素

[Physical exertion tolerance and its determining factors in hypertrophic cardiomyopathy].

作者信息

Storozhakov G I, Selivanov A I, Kisliak O A, Gendlin G E, Kopelev A M, Savitskaia O V

出版信息

Kardiologiia. 1991 May;31(5):52-6.

PMID:1895649
Abstract

A contribution of specific features of myocardial hypertrophy and hypercontractility left ventricular diastolic dysfunction to decreased exercise tolerance and developed coronary failure is discussed on the basis of results obtained from a bicycle ergometric test performed in 40 patients with hypertrophic cardiomyopathy. Thallium-201 myocardial scintigraphy conducted at the maximum exercise in 17 patients revealed a reduction in coronary reserve with increased myocardial mass index that was higher than the critical value. An implication of severe myocardial hypertrophy in the presence with coexisting left ventricular posterior wall hypertrophy and impaired perfusion/mass ratios is considered as a risk factor for death of patients with hypertrophic cardiomyopathy.

摘要

基于对40例肥厚型心肌病患者进行的自行车测力计测试结果,讨论了心肌肥厚和高收缩性左心室舒张功能障碍的特定特征对运动耐力下降和发生冠状动脉衰竭的影响。对17例患者在最大运动量时进行的铊-201心肌闪烁显像显示,随着心肌质量指数增加超过临界值,冠状动脉储备减少。严重心肌肥厚合并左心室后壁肥厚及灌注/质量比受损被认为是肥厚型心肌病患者死亡的危险因素。

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