Kek Khai Jun, Kibe Ryuta, Niwayama Masatsugu, Kudo Nobuki, Yamamoto Katsuyuki
Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Japan.
Opt Express. 2008 Oct 27;16(22):18173-87. doi: 10.1364/oe.16.018173.
An imaging instrument based on spatially resolved spectroscopy that enables temporal and spatial analyses of muscle oxygenation was designed. The instrument is portable and can be connected to 32 compact and separate-type optical probes. Its measurement accuracy of O(2) saturation and hemoglobin concentration was evaluated using a tissue-equivalent phantom. Imaging and multi-point measurements of tissue oxygen saturation (S(t)O(2)) in the quadriceps muscle were also performed, and dynamic changes in S(t)O(2) in response to increase in exercise intensity (within the rectus femoris region) and variation in exercise protocol (among the rectus femoris, vastus lateralis and vastus medialis) were clearly shown.
设计了一种基于空间分辨光谱学的成像仪器，可对肌肉氧合进行时空分析。该仪器便于携带，可连接32个紧凑的独立式光学探头。使用组织等效体模评估了其对氧饱和度和血红蛋白浓度的测量精度。还对股四头肌的组织氧饱和度（S(t)O(2)）进行了成像和多点测量，清晰显示了运动强度增加（在股直肌区域内）和运动方案变化（在股直肌、股外侧肌和股内侧肌之间）时S(t)O(2)的动态变化。
