Poe D S, Jackson G, Glasscock M E, Johnson G D
Department of Otolaryngology-Head and Neck Surgery, Lahey Clinic Medical Center, Burlington, MA 01805.
Laryngoscope. 1991 Apr;101(4 Pt 1):372-8. doi: 10.1002/lary.1991.101.4.372.
The surgical management of patients with slow-growing benign temporal bone neoplasms has been criticized because of its significant morbidity and mortality compared with results after radiation therapy, but long-term control by irradiation remains unproved. Long-term surgical results have not been studied previously. One hundred twenty-nine skull base operations were performed in 126 patients at the Otology Group, Nashville, Tenn., from January 1970 through May 1987. Fifty-eight patients responded to questionnaires focusing on recovery from loss of cranial nerves. All patients regained some degree of facial function (class V or better), no alimentary tubes or tracheotomies were in use, and no patients had debilitating aspiration. Long-term compensation from the cranial nerve deficits of lateral skull base surgery can be expected in most patients and should not be used as an argument for irradiation in patients with a long life expectancy at time of diagnosis.
生长缓慢的颞骨良性肿瘤患者的手术治疗受到批评,因为与放射治疗后的结果相比,其具有显著的发病率和死亡率,但放射治疗的长期控制效果尚未得到证实。此前尚未对长期手术结果进行研究。1970年1月至1987年5月期间,田纳西州纳什维尔耳科学组对126例患者进行了129次颅底手术。58例患者回复了关注从颅神经损伤恢复情况的问卷。所有患者均恢复了一定程度的面部功能(V级或更好),未使用鼻饲管或气管切开术,也没有患者出现使人虚弱的误吸。大多数患者可以预期从外侧颅底手术的颅神经缺损中获得长期代偿,并且在诊断时预期寿命较长的患者中,不应将其作为支持放射治疗的论据。