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[头颈部副神经节瘤的诊断与治疗回顾及展望]

[Review and prospect of the diagnosis and treatment of head and neck paragangliomas].

作者信息

Yin Shankai

机构信息

Department of Otorhinolaryngology,Shangha Sixth People's Hospital and Shanghai Jiao Tong University School of Medicine,Shanghai,200233,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Sep;38(9):773-776. doi: 10.13201/j.issn.2096-7993.2024.09.001.

DOI:10.13201/j.issn.2096-7993.2024.09.001
PMID:39193732
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11839586/
Abstract

ead and neck paraganglioma(HNPGL) often originates from the parasympathetic ganglia and is a highly invasive benign tumor. The diagnosis and treatment of this disease with strong heterogeneity is still a challenge. In the future, deep exploration is needed in genetic typing, grading diagnosis and treatment decisions, protection of cranial nerves and new drug treatments to better treat this disease.

摘要

头颈部副神经节瘤(HNPGL)常起源于副交感神经节,是一种具有高度侵袭性的良性肿瘤。对这种具有高度异质性的疾病进行诊断和治疗仍然是一项挑战。未来,需要在基因分型、分级诊断与治疗决策、脑神经保护及新药治疗等方面进行深入探索,以更好地治疗这种疾病。

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本文引用的文献

1
Modern Management of Complex Tympanojugular Paragangliomas: Systematic Review and Meta-Analysis.复杂鼓室-颈静脉鼓室副神经节瘤的现代治疗方法:系统评价和荟萃分析。
World Neurosurg. 2023 Feb;170:149-156.e3. doi: 10.1016/j.wneu.2022.11.037. Epub 2022 Nov 16.
2
Paraganglioma of the Head and Neck: A Review.头颈部副神经节瘤:综述。
Endocr Pract. 2023 Feb;29(2):141-147. doi: 10.1016/j.eprac.2022.10.002. Epub 2022 Oct 15.
3
[Application of internal carotid artery stent in skull base surgery].[颈内动脉支架在颅底手术中的应用]
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Jul 7;57(7):835-842. doi: 10.3760/cma.j.cn115330-20210707-00434.
4
Head and Neck Paragangliomas: An Update on the Molecular Classification, State-of-the-Art Imaging, and Management Recommendations.头颈部副神经节瘤:分子分类、最新成像技术和管理建议的更新。
Radiol Imaging Cancer. 2022 May;4(3):e210088. doi: 10.1148/rycan.210088.
5
Belzutifan, a Potent HIF2α Inhibitor, in the Pacak-Zhuang Syndrome.贝伐珠单抗,一种有效的 HIF2α 抑制剂,在 Pacak-Zhuang 综合征中的应用。
N Engl J Med. 2021 Nov 25;385(22):2059-2065. doi: 10.1056/NEJMoa2110051.
6
British Skull Base Society Clinical Consensus Document on Management of Head and Neck Paragangliomas.英国颅底外科协会关于头颈部副神经节瘤治疗的临床共识文件。
Otolaryngol Head Neck Surg. 2020 Sep;163(3):400-409. doi: 10.1177/0194599820915490. Epub 2020 Apr 28.
7
External beam radiation therapy for advanced/unresectable malignant paraganglioma and pheochromocytoma.晚期/不可切除恶性副神经节瘤和嗜铬细胞瘤的外照射放射治疗
Adv Radiat Oncol. 2017 Nov 22;3(1):25-29. doi: 10.1016/j.adro.2017.11.002. eCollection 2018 Jan-Mar.
8
Mitochondrial metabolic remodeling in response to genetic and environmental perturbations.线粒体代谢重塑对遗传和环境扰动的响应。
Wiley Interdiscip Rev Syst Biol Med. 2016 Jul;8(4):272-85. doi: 10.1002/wsbm.1334. Epub 2016 May 19.
9
Strategies and long-term outcomes in the surgical management of tympanojugular paragangliomas.鼓室球瘤手术治疗的策略及长期疗效
Head Neck. 2016 Jun;38(6):871-85. doi: 10.1002/hed.24177. Epub 2015 Sep 7.
10
Hypoxia-inducible factor signaling in pheochromocytoma: turning the rudder in the right direction.缺氧诱导因子信号在嗜铬细胞瘤中的作用:把握正确的方向。
J Natl Cancer Inst. 2013 Sep 4;105(17):1270-83. doi: 10.1093/jnci/djt201. Epub 2013 Aug 12.