Serum triglyceride and cholesterol levels and lipid electrophoretic patterns in intrinsic and extrinsic allergic states.

This study indicates that hypertriglyceridemia and associated pre-beta hyperlipidemia (Fredrickson's type IV lipid pattern) is frequently associated with intrinsic allergic disease characterized by chemical intolerant (hypersensitivity) states, particularly of the aspirin intolerant type and to a somewhat lesser extent with the butylated hydroxyanisole and butylated hydroxytoluene intolerant type, as well as the iodide intolerant state. It confirms that diabetics suffering concomitantly with extrinsic or intrinsic allergic disease still continue to demonstrate a high occurrence of this type of hypertriglyceridemia. In contrast, pure atopic, extrinsic-allergic patients demonstrated a very low incidence of type IV hyperlipoproteinemia. The interrelationships of these findings with previously reported metabolic abnormalities in intrinsic allergic hypersensitivity states is correlated.