Wendt J R
Irvine Medical Center, University of California.
Plast Reconstr Surg. 1991 Oct;88(4):713-7. doi: 10.1097/00006534-199110000-00026.
A fresh-frozen thumb osteoarthrotendinous allograft and autogenous coverage were used to reconstruct a thumb. Immunosuppressants were not used. The components of the composite allograft are present and functioning 1 year post-operatively. Host cells have replaced and are replacing bone and tendinous structures. The "survival" of this osteoarthrotendinous allograft may have important implications in the treatment of patients with previous digital amputations, congenital absence of digits, and amputated digits that have failed replantation or are not replantable because of severely damaged vessels.
采用新鲜冷冻的拇指骨关节肌腱同种异体移植物和自体覆盖物重建拇指。未使用免疫抑制剂。术后1年,复合异体移植物的各成分存在且功能良好。宿主细胞已取代并正在取代骨和肌腱结构。这种骨关节肌腱同种异体移植物的“存活”可能对既往手指截肢、先天性手指缺失以及因血管严重受损而未能再植或无法再植的截肢手指患者的治疗具有重要意义。