Lagalla R, Iovane A, Caruso G, Midiri M, Oliveri D, Brancato G, Cardinale A
Cattedra di Radiologia, Università degli Studi, Palermo.
Radiol Med. 1991 Jul-Aug;82(1-2):70-2.
The authors report their experience in the study of 8 patients showing symptoms of thyroid hyperfunction (Plummer's adenoma) and treated with US-guided percutaneous ethanol injection. The treatment consisted in injecting sterile ethanol in varying amounts (2 to 5 ml) according to nodule size, using a fine needle under US guidance. The patients underwent 3 to 6 injections, according to biochemical (T3-T4-TSH) and scintigraphic findings. Follow-up at 12 months showed regression of clinical symptoms, a trend of hormone levels toward normalization and recovery of previously suppressed parenchymal function. No significant complications were observed, except for a transient thyrotoxic crisis in the patient bearing the largest nodule. The treatment of Plummer's adenoma by means of percutaneous ethanol injection under US guidance appears to provide specific clinical and technical advantages over other conventional treatments.
作者报告了他们对8例表现出甲状腺功能亢进症状（普拉默腺瘤）并接受超声引导下经皮乙醇注射治疗的患者的研究经验。治疗方法是在超声引导下，使用细针根据结节大小注射不同剂量（2至5毫升）的无菌乙醇。根据生化指标（T3 - T4 - TSH）和闪烁扫描结果，患者接受了3至6次注射。12个月的随访显示临床症状消退，激素水平趋于正常化，先前受抑制的实质功能恢复。除了最大结节的患者出现短暂甲状腺毒症危象外，未观察到明显并发症。超声引导下经皮乙醇注射治疗普拉默腺瘤似乎比其他传统治疗方法具有特定的临床和技术优势。
