de Peyer E, Rouge J C, Sizonenko P C, Paunier L
Ann Anesthesiol Fr. 1977;18(2):205-13.
Magnesium plays an essential role in the processes of myocardial contraction and conduction. In cardiovascular surgery, extracorporeal circulation (ECC) in haemodilution results in various electrolyte distrubances, with invariably hypomagnesaemia. A group of 13 children undergoing open heart surgery was compared with a group of 17 children operated upon under the same conditions but with the addition of magnesium to the filling solution for the extracorporeal circulation. Changes in blood and urinary electrolytes during and after ECC were studied. Hypomagnesaemia was seen in both groups after surgery but the provision of magnesium supplements shortened the duration. In addition, blood phosphate levels remained significantly higher in the group receiving magnesium. The significance of these various findings is discussed and a technique for the provision of magnesium supplements is proposed.
镁在心肌收缩和传导过程中起着至关重要的作用。在心血管手术中,体外循环(ECC)导致血液稀释,进而引发各种电解质紊乱,其中低镁血症是必然出现的。将一组接受心脏直视手术的13名儿童与另一组17名在相同条件下进行手术但在体外循环填充液中添加了镁的儿童进行比较。研究了体外循环期间及之后血液和尿液电解质的变化。两组术后均出现低镁血症,但补充镁缩短了低镁血症持续时间。此外,接受镁补充的组中血磷水平仍显著更高。文中讨论了这些不同发现的意义,并提出了补充镁的技术。